Results 11 to 20 of about 1,827,826 (348)

Delivery technologies for human vaccines [PDF]

British Medical Bulletin, 2002
There is currently intense research activity aimed at the development of new delivery systems for vaccines. The goal is to identify optimal methods for presenting target antigens to the immune system in a manner that will elicit immune responses appropriate for protection against, or treatment of, a specific disease.
Philippe, Moingeon, Charles, de Taisne, Jeffrey, Almond   +2 more
openaire   +2 more sources

Global Delivery of Human Papillomavirus Vaccines [PDF]

Pediatric Clinics of North America, 2016
Worldwide, cervical cancer is the fourth most common cancer among women. Human papillomavirus (HPV) vaccination, if broadly implemented, has the potential to significantly reduce global rates of morbidity and mortality associated with cervical and other HPV-related cancers. More than 100 countries around the world have licensed HPV vaccines.
Wigle, Jannah, Fontenot, Holly B., Zimet, Gregory D.   +2 more
openaire   +2 more sources

RNA Aptamer Delivery through Intact Human Skin [PDF]

Journal of Investigative Dermatology, 2018
It is generally recognized that only relatively small molecular weight (typically < ∼ 500 Da) drugs can effectively permeate through intact stratum corneum. Here, we challenge this orthodoxy using a 62-nucleotide (molecular weight = 20,395 Da) RNA-based aptamer, highly specific to the human IL-23 cytokine, with picomolar activity.
Jon D. Lenn, Jessica Neil, Christine Donahue, Kellie Demock, Caitlin Vestal Tibbetts, Javier Cote-Sierra, Susan H. Smith, David Rubenstein, Jean-Philippe Therrien, P. Shannon Pendergrast, Jason Killough, Marc B. Brown, Adrian C. Williams   +12 more
openaire   +2 more sources

Intracoronary Heparin Delivery in Humans [PDF]

Circulation, 1995
Background Inefficacy of systemic drug administration for restenosis prevention may partially relate to insufficient local drug concentration. This study aimed to evaluate the acute feasibility and long-term outcome of using an infusion-perfusion coil balloon, Dispatch. Methods and Results
Camenzind, Edoardo, Kint, Peter Paul, Di Mario, Carlo, Ligthart, Jürgen, Van Der Giessen, Wim, Boersma, Eric, Serruys, Patrick W.   +6 more
openaire   +2 more sources

Práticas sociais de medicalização & humanização no cuidado de mulheres na gestação

Cadernos de Saúde Pública, 2018
Resumo: O objetivo principal do trabalho é analisar como discursos de medicalização & humanização se (re)articulam na atenção primária em saúde e configuram o cuidado pré-natal de mulheres grávidas realizado por equipes de saúde da família.
Cristine Maria Warmling, Ananyr Porto Fajardo, Dagmar Estermann Meyer, Cristophe Bedos   +3 more
doaj   +1 more source

“Giving birth is not a matter of ethnicity, it is a matter of humanity”: experiences of obstetric violence during childbirth among indigenous women

Salud Colectiva, 2021
This study aims to understand the experiences of obstetric violence experienced by Embera women during childbirth at healthcare facilities in the city of Medellin, Colombia.
Emily Gaffney Gleason, Diana Patricia Molina Berrío, Jennifer Marcela López Ríos, Cristina María Mejía Merino   +3 more
doaj   +1 more source

Educational technology to promote father involvement in childbirth and birth

Revista Brasileira de Enfermagem, 2022
Objectives: to build and validate an educational booklet to promote the involvement of parents in labor and birth. Methods: methodological study developed in five stages: situational diagnosis; bibliographic survey; construction of illustrations, layout,
Guilherme Frederico Abdul Nour, Maria Adelane Monteiro da Silva, Ana Jessyca Campos Sousa, Andréa Carvalho Araújo Moreira, Cibelly Aliny Siqueira Lima Freitas, Tatiane da Silva Coelho, Juliana Oliveira Brito, Ana Kelve de Castro Damasceno   +7 more
doaj   +2 more sources

Delivery of Active AKT1 to Human Cells

Cells, 2022
Protein kinase B (AKT1) is a serine/threonine kinase and central transducer of cell survival pathways. Typical approaches to study AKT1 biology in cells rely on growth factor or insulin stimulation that activates AKT1 via phosphorylation at two key regulatory sites (Thr308, Ser473), yet cell stimulation also activates many other kinases.
Tarana Siddika, Nileeka Balasuriya, Mallory I. Frederick, Peter Rozik, Ilka U. Heinemann, Patrick O’Donoghue   +5 more
openaire   +3 more sources

Puerperal women's perceptions on vertical and horizontal deliveries Percepciones de puérperas sobre la vivencia durante el parto en la posición vertical y horizontal Percepções de puérperas sobre a vivência de parir na posição vertical e horizontal

Revista Latino-Americana de Enfermagem, 2009
This qualitative study aims to better understand the perceptions of puerperal women regarding their experiences in vertical and horizontal deliveries and identify positive and negative aspects of each position. Semi-structured interviews were carried out
Michele Edianez Gayeski, Odaléa Maria Brüggemann   +1 more
doaj   +1 more source

SKIN-TO-SKIN CONTACT AND BREASTFEEDING AT CHILDBIRTH: WOMEN’S DESIRES, EXPECTATIONS, AND EXPERIENCES

Revista Paulista de Pediatria, 2021
Objective: To analyze women’s desires, expectations and experiences regarding skin-to-skin contact and breastfeeding in the first hour of life of their newborns.
Alice Parentes da Silva Santos, Zeni Carvalho Lamy, Maria Eduarda Koser, Clarice Maria Ribeiro de Paula Gomes, Beatriz Matos Costa, Laura Lamas Martins Gonçalves   +5 more
doaj   +2 more sources