Results 251 to 260 of about 1,667 (307)

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Plant-Based Strategies for Vaccine Development: A Narrative Review of Recombinant Biofactories, Phytochemical Adjuvants, Innovative Delivery Systems, and Insights on Oral and Edible Vaccines. [PDF]

Vaccines (Basel)
Najafi K, Jojani M, Najafi S, Roviello GN.   +3 more
europepmc   +1 more source

Navigating Ethical Review Processes in Conflict‐Affected, Authoritarian Contexts: A Case Study of Myanmar's Interim Ethics Review Board (IERB)

Asia Pacific Viewpoint, EarlyView.
ABSTRACT This article examines the formation and operation of Myanmar's Interim Ethics Review Board (IERB), which was established in November 2023 by displaced academics involved in the Civil Disobedience Movement against the 2021 military coup. Operating within a highly repressive, conflict‐ridden environment, the IERB exemplifies a locally‐led and ...
Phyu Phyu Thin Zaw, Su Su Maw, Nyein Chan, The Spring IERB Team   +3 more
wiley   +1 more source

Who Is That Cardiology Fellow? A Cluster Trial Examining the Impact of Cardiology Fellows' Biographical Information on Patient Perceptions of Patient-Centered Care. [PDF]

J Am Heart Assoc
Force Z, Martin CD, Hashmath Z, Fernandes R, Iqbal M, Kosaraju A, Qavi A, Pandya D, Samaan S, Singh C, Khant K, Sankaramangalam K, Udani K, Singh A, Nekkanti R, Sears SF.   +15 more
europepmc   +1 more source

Midwifery Care Studies: A Reflexive Methodology for a Practice‐Based Science

Birth, EarlyView.
Introducing Midwifery Care Studies: a novel reflexive approach examining midwifery as practice‐based science. ABSTRACT Background Midwifery research is increasingly understood as shaped by the specific social, political, and historical contexts, with scientific practices actively co‐producing realities.
Annekatrin Skeide
wiley   +1 more source

Voices from the ICU: Perspectives on Humanization in Critical Care Settings. [PDF]

Indian J Crit Care Med
Paul G, Mahajan RK, Gautam PL, Kaur G, Paul SS, Paul B.   +5 more
europepmc   +1 more source

Prevalence of Episiotomy Practice and Associated Factors in Brazil: A Systematic Review

Birth, EarlyView.
ABSTRACT Introduction Although routine episiotomy is not recommended, it remains widely performed during childbirth, with rates varying substantially across countries. This systematic review synthesizes evidence on the prevalence and associated factors of episiotomy in Brazil.
Ana Carolina dos Santos Rodrigues, Maria Luziene de Sousa Gomes, Roger Rodrigues da Silva, Eremita Val Rafael, Patrícia Ribeiro Azevedo, Claudia Teresa Frias Rios, Janielle Ferreira de Brito Lima, Mônica Oliveira Batista Oriá   +7 more
wiley   +1 more source

Beyond Pain Management: Skin-to-Skin Contact as a Humanization Strategy in Cesarean Delivery: A Randomized Controlled Trial. [PDF]

Healthcare (Basel)
Pérez-Jiménez JM, de-Diego-Cordero R, Borrallo-Riego Á, Luque-Oliveros M, de-Pedro-Jimenez D, Coheña-Jimenez M, Sierra PB, Guerra-Martín MD.   +7 more
europepmc   +1 more source

Thrombocytosis and the generation of platelet‐derived microparticles in the pathophysiology of sickle cell disease

British Journal of Haematology, EarlyView.
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê, Anna Dillon, Owen P. Smith, Corrina McMahon   +3 more
wiley   +1 more source

Exploring staff and service user experiences of personality disorder services in open prisons: A qualitative study of Pathways Enhanced Resettlement Support. [PDF]

PLoS One
Mathlin G, Jones H, Lewis C, Cooper C, Freestone M.   +4 more
europepmc   +1 more source