Results 101 to 110 of about 174,519 (291)
Interpreting human life by looking the other way: Bonhoeffer on human beings and other animals [PDF]
, 2010 This is the author's pdf version of the book ...
Clough, David
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Eco-theological anthropology in Christianity: imago Dei and ecological preservation
HTS Teologiese Studies/Theological StudiesGenesis 1:26 states that humankind has been created in the image of God. There are three general interpretations of what this means. While the substantial view emphasises the essence of humankind and the relational view underscores the social aspect, the
Ismail Lala
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Conservation of Biodiversity- A Humankind Necessity
International Journal of Economic Plants, 2014 This short communication provides a basic description of biodiversity, principles for its conservation, and particular drivers for its loss. It alsoprovides an outline of the international efforts that lead the way to biodiversity conservation and ideas
Oscar Roberto Murga Solares
doaj
The Costs of the Sustainable Development at the Beginning of the 3rd Millennium [PDF]
Presently the climate changes at a global level show, from the point of view of the effects that they generate a great importance. The real threat for the human survival is not the terrorism, but the climate changes determined by the global warmth.
George CIOBANU +1 more
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What’s Left of Human Nature? A Post-Essentialist, Pluralist and Interactive Account of a Contested Concept [PDF]
, 2018 Human nature has always been a foundational issue for philosophy. What does it mean to have a human nature? Is the concept the relic of a bygone age? What is the use of such a concept?
Kronfeldner, Maria
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source