Results 111 to 120 of about 19,747,875 (398)
The Monogamy Gene Could Also Act in Humans [PDF]
, 2008 Research has revealed that genetic variations in the human gene AVPR1A affect the disposition and aptitude of individuals to live in a relationship. Thus the activity of this gene could influence the quality of marital relationships and very likely our ...
Chad Eliason (4420921) +2 more
core +2 more sources
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Scientific ReportsDeep neural networks (DNNs) excel at extracting insights from complex data across various fields, however, their application in cognitive neuroscience remains limited, largely due to the lack of approaches with interpretability.
Murat Kucukosmanoglu +3 more
doaj +1 more source
Location, location, location: Tissue resident memory T cells in mice and humans
Science immunology, 2019 This review summarizes key studies that have shaped our understanding of tissue resident memory T cells in mice and humans. The discovery of T cells resident in diverse tissues has altered our understanding of adaptive immunity to encompass site-specific
P. Szabo, M. Miron, D. Farber
semanticscholar +1 more source
The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells
FEBS Letters, EarlyView.The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman +3 more
wiley +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Checking chess checks with chunks: A model of simple check detection [PDF]
, 2009 The procedure by which humans identify checks in check positions is not well understood. We report here our experience in modelling this process with CHREST, a general-purpose cognitive model that has previously successfully captured a variety of ...
Gobet, F, Lane, PCR, Smith, RL
core
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Journal of biomedical discovery and collaboration, 2006 Scientific and popular lore have promulgated a connection between emotion and the limbic forebrain. However, there are a variety of structures that are considered limbic, and disagreement as to what is meant by "emotion". This essay traces the initial studies upon which the connection between emotion and the limbic forebrain was based and how ...
openaire +2 more sources