Results 161 to 170 of about 19,747,875 (398)

Cobots in Industry 4.0: A Roadmap for Future Practice Studies on Human–Robot Collaboration [PDF]

, 2021
Astrid Weiss, Ann-Kathrin Wortmeier, Bettina Kubicek   +2 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Teacher Training as an Obligation to Prevent Sexual Violence against Children: Meeting International Standards

Age of Human Rights Journal
This paper holds that teacher training constitutes a binding preventive obligation arising from Articles 19 and 34 of the Convention on the Rights of the Child, Article 5 of the Lanzarote Convention, and Article 23(3) of Directive 2011/92/EU ...
Alejandra Ramírez González
doaj   +1 more source

Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders

, 2022
Julien Bryois, Daniela Calini, Will Macnair, Lynette C. Foo, Eduard Urich, Ward Ortmann, Victor A. Iglesias, Suresh Selvaraj, Erik Nutma, Manuel Marzin, Sandra Amor, Anna Williams, Gonçalo Castelo‐Branco, Vilas Menon, Philip L. De Jager, Dheeraj Malhotra   +15 more
openalex   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Modulating parameters of excitability during and after transcranial direct current stimulation of the human motor cortex

, 2005
Michael A. Nitsche, A Seeber, Kai Frommann, Cornelia Carmen Klein, Christian Rochford, Maren S. Nitsche, K. Fricke, David Liebetanz, Nicolas Lang, Andrea Antal, Walter Paulus, Frithjof Tergau   +11 more
openalex   +2 more sources

Serum immunoreactive-leptin concentrations in normal-weight and obese humans.

New England Journal of Medicine, 1996
R. Considine, M. Sinha, M. Heiman, A. Kriauciunas, T. Stephens, M. Nyce, Joanna P. Ohannesian, Cheryl C. Marco, L. McKee, T. L. Bauer, J. Caro   +10 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

, 2015
Fiona Cuskin, Elisabeth C. Lowe, Max J. Temple, Yanping Zhu, Elizabeth A. Cameron, Nicholas A. Pudlo, Nathan T. Porter, Karthik Urs, Andrew J. Thompson, Alan Cartmell, Artur Rogowski, Brian S. Hamilton, Rui Chen, Thomas J. Tolbert, Kathleen Piens, Debby Bracke, Wouter Vervecken, Z. Hakki, Gaetano Speciale, José Muñoz-Muñoz, Andrew Day, María J. Peña, Richard P. McLean, M.D.L. Suits, A.B. Boraston, Todd Atherly, Cherie J. Ziemer, Spencer J. Williams, G.J. Davies, D. Wade Abbott, Eric C. Martens, Harry J. Gilbert   +31 more
openalex   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source