Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy [PDF]
, 2018 Diogo Mosqueira +16 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
The «suitability» criteria implemented on the migrant’s housing rights: a changeable geometry
Migraciones, 2014 The universal scope of the suitable concept and the minimal content of housing rights has been developed by the Committee on Economic, Social and Cultural Rights.
Encarnación Encarnación La Spina
doaj
Simulating Problem Difficulty in Arithmetic Cognition Through Dynamic Connectionist Models
, 2019 The present study aims to investigate similarities between how humans and connectionist models experience difficulty in arithmetic problems. Problem difficulty was operationalized by the number of carries involved in solving a given problem.
Cho, Sungjae +4 more
core
Accumulation of nanoparticles in the soil-plant systems and their effects on human health
, 2020 Vishnu D. Rajput +9 more
openalex +1 more source
Persistence of the mitochondrial permeability transition in the absence of subunit c of human ATP synthase [PDF]
, 2017 Jiuya He +5 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Telomere Erosion and Senescence in Human Articular Cartilage Chondrocytes [PDF]
, 2001 James A. Martin, Joseph A. Buckwalter
openalex +1 more source
Toxoplasma gondii: from animals to humans.
International Journal of Parasitology, 2000 A. Tenter, A. Heckeroth, L. Weiss
semanticscholar +1 more source