Results 51 to 60 of about 68,793 (234)

Humidifier disinfectant disaster: what is known and what needs to be clarified [PDF]

open access: yesEnvironmental Health and Toxicology, 2016
After the initial investigations by the Korea Centers for Disease Control in 2011, over 1000 suspicious cases of humidifier disinfectant (HD) victims were subsequently reported by 2015, and numbers are still increasing dramatically in 2016 in the midst of the prosecutors' office investigation. This study attempts to summarize the current understandings
Sungkyoon Kim, Domyung Paek
openaire   +3 more sources

Hematotoxic Effect of Respiratory Exposure to PHMG-p and Its Integrated Genetic Analysis

open access: yesToxics, 2022
Polyhexamethylene guanidine phosphate (PHMG-p), the main ingredient of humidifier disinfectants, circulates systemically through the lungs; however, its toxicological assessment has been primarily limited to pulmonary disease. Herein, we investigated the
Hwa Jung Sung   +12 more
doaj   +1 more source

The humidifier disinfectant case and the legislative challenges of the 20th Congress [PDF]

open access: yesEnvironmental Health and Toxicology, 2016
A number of absurdities surrounding the humidifier disinfectant (HD) incident may have occurred because 1) a judicial system operates on the underlying false assumption that the involved parties are equals in knowledge, information and resource mobilization capabilities, regardless of respective real status as company or individual; 2) there is a lack ...
openaire   +3 more sources

An analysis of a humidifier disinfectant case from a toxicological perspective [PDF]

open access: yesEnvironmental Health and Toxicology, 2016
An analysis of patients and fatalities due to exposure to polyhexamethylene guanidine (PHMG) shows that PHMG causes mainly lung diseases such as pulmonary fibrosis. However, no research on the other organs has been conducted on this matter yet. So, an in-depth discussion on toxicological techniques is needed to determine whether or not PHMG is toxic to
openaire   +3 more sources

Humidifier Disinfectant–associated Children’s Interstitial Lung Disease

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2014
Abstract Rationale Beginning in 2006, epidemics of a fatal lung injury of unknown cause in children were observed in Korea every spring. A recent study demonstrated that this type of children’s interstitial lung disease (chILD) is associated with humidifier disinfectant use.
Kyung Won, Kim   +33 more
openaire   +3 more sources

Intratracheal exposure to polyhexamethylene guanidine phosphate disrupts coordinate regulation of FXR-SHP-mediated cholesterol and bile acid homeostasis in mouse liver

open access: yesEcotoxicology and Environmental Safety, 2022
A public health crisis in the form of a significant incidence of fatal pulmonary disease caused by repeated use of humidifier disinfectants containing polyhexamethylene guanidine phosphate (PHMG) recently arose in Korea.
You-Jin Choi   +10 more
doaj   +1 more source

Mental health impact on a humidifier disinfectant disaster victim: a case report [PDF]

open access: yesAnnals of Occupational and Environmental Medicine, 2020
In Korea, the cause of lung disease of unknown origin was identified as humidifier disinfectants in November 2011. In February 2017, the 'Special Act on Remedy for Damage Caused by Humidifier Disinfectants' was promulgated. Even though emotional and mental injuries caused by humidifier disinfectants have been reported, the focus of the special act has ...
Ye-Sung Lee   +5 more
openaire   +2 more sources

Health Effects Associated With Humidifier Disinfectant Use: A Systematic Review for Exploration

open access: yesJournal of Korean Medical Science, 2022
It has been 10 years since the outbreak of lung disease caused by humidifier disinfectants in Korea, but the health effects have not yet been summarized. Therefore, this study aims to systematically examine the health effects of humidifier disinfectants that have been discovered so far.All literature with humidifier disinfectants and their ...
Ji-Hun Song   +7 more
openaire   +3 more sources

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

open access: yesAdvanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim   +9 more
wiley   +1 more source

Early-life exposure to humidifier disinfectant determines the prognosis of lung function in children

open access: yesBMC Pulmonary Medicine, 2019
Background Use of humidifier disinfectants (HD) at home leads to chemical airborne exposure, causing HD associated lung injury (HDLI) with high mortality. However, the lung function in children diagnosed with HDLI is not well studied. We investigated the
Hyun-Ju Cho   +8 more
doaj   +1 more source

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