Results 11 to 20 of about 1,440,932 (242)

Domestic ventilation rates, indoor humidity and dust mite allergens : are our homes causing the asthma pandemic? [PDF]

, 2003
This paper is concerned with historical changes in domestic ventilation rates, relative humidity and the associated risk of house dust mite colonization.
A Lawson, Arlian LG, Asselt L, BRE, C McSharry, Clarke JA, Cornish JP, Coward SKD, Crowther D, E McKenzie, Etheridge DW, G Morris, Garratt J, Gunnerson L, J Jackson, Lynden van Nes AMT, McMaster University, S G Howieson, Scottish Homes, Stephen RK, Tovey ER, Tovey ER   +21 more
core   +1 more source

Modeling ambient temperature and relative humidity sensitivity of respiratory droplets and their role in Covid-19 outbreaks [PDF]

, 2020
One of the many unresolved questions that revolves around the Covid-19 pandemic is whether local outbreaks can depend on ambient conditions like temperature and relative humidity.
Basu, Saptarshi, Chaudhuri, Swetaprovo, Kabi, Prasenjit, Saha, Abhishek, Unni, Vishnu R.   +4 more
core   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Relative Humidity Protocol [PDF]

, 2003
The purpose of this activity is to measure relative humidity using both a sling psychrometer and a digital hygrometer. Intended outcomes are that students learn to quantify humidity and that there is a limit to the amount of water vapor that the air can ...
The GLOBE Program, UCAR (University Corporation for Atmospheric Research)
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Millimeter-wave atmospheric loss prediction method [PDF]

, 1969
Relationship between atmospheric attenuation and the ground temperature and humidity provides a reference from which changes in temperature and humidity will produce a corresponding atmospheric loss figure.
Stelzried, C. T.
core   +1 more source

The Relative Humidity in an Isentropic Advection–Condensation Model: Limited Poleward Influence and Properties of Subtropical Minima [PDF]

, 2011
An idealized model of advection and condensation of water vapor is considered as a representation of processes influencing the humidity distribution along isentropic surfaces in the free troposphere.
Boer, Bolton, Couhert, Derbyshire, Dessler, Frierson, Frierson, Galewsky, Held, Held, Hurley, Hurley, Martin S. Singh, Mitchell, Nicolas Lamquin, O’Gorman, O’Gorman, O’Gorman, Paul A. O’Gorman, Pierrehumbert, Pierrehumbert, Pierrehumbert, Salathé, Schneider, Schneider, Schneider, Schneider, Seidel, Sherwood, Sherwood, Sherwood, Smith, Sukhatme, Tapio Schneider, Thomson, Uppala, Wright, Yang   +37 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source