Results 31 to 40 of about 564,713 (260)

Physical-Mechanical Properties of Waterproofing Materials Applied to Roofs in the Context of UV Degradation

Slovak Journal of Civil Engineering, 2022
The subject of the article is a physical-mechanical analysis of waterproofing materials exposed to an external environment. Physical and mechanical properties have a direct impact on the life of waterproofing materials and their later remediation. In the
Kováč Jozef, Palko Milan, Kleinová Angela   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Fuzzy logic device for crop analysing, modeling and forecasting in the Kabardino-Balkarian Republic

RUDN Journal of Agronomy and Animal Industries, 2020
Using computer fuzzy-logical models based on empirical values of climatic characteristics (rainfall, temperature and humidity) of long-term observations (1955-2018) from meteorological stations in the Kabardino-Balkarian Republic (Nalchik, Baksan ...
Ruslan M. Bischokov
doaj   +1 more source

Harnessing Terrestrial Laser Scanning for Monitoring of Saturation of Buildings [PDF]

Biuletyn Wojskowej Akademii Technicznej, 2017
A type of scanned surface (its physico-chemical properties) significantly influences the power of the returning laser signal in terrestrial laser scanner technique.
Czesław Suchocki, Jacek Katzer, Marzena Damięcka-Suchocka, Elżbieta Kuźmińska, Jacek Rapiński   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Home humidity increased risk of tuberculosis in children living with adult active tuberculosis cases [PDF]

Universa Medicina, 2011
Indonesia is one of the countries with the largest number of tuberculosis (TB) cases in the world. Environmental factors play significant roles in infection and disease development in children living with adult active TB cases.
Pudji Lestari, Florentina Sustini, Anang Endaryanto, Retno Asih   +3 more
doaj  

Development of metrological support for quantitative NMR analyzers

Стандартные образцы, 2019
The first part of the article presents the history of creating quantitative NMR analyzers of oil content and humidity of oil crop seeds and their by-products.
S. M. Prudnikov, B. Ya. Vityuk, O. S. Agafonov   +2 more
doaj   +1 more source

Correction Model for Metal Oxide Sensor Drift Caused by Ambient Temperature and Humidity

Sensors, 2022
For decades, Metal oxide (MOX) gas sensors have been commercially available and used in various applications such as the Smart City, gas monitoring, and safety due to advantages such as high sensitivity, a high detection range, fast reaction time, and ...
Abdulnasser Nabil Abdullah, Kamarulzaman Kamarudin, Latifah Munirah Kamarudin, Abdul Hamid Adom, Syed Muhammad Mamduh, Zaffry Hadi Mohd Juffry, Victor Hernandez Bennetts   +6 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source