Results 121 to 130 of about 1,002,942 (309)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Sixty day manned evaluation of zero gravity humidity control system [PDF]

open access: yes
Manned evaluation of zero gravity humidity control system in potable water recovery unit for simulated spacecraft ...
Joy, R. W., Olcott, T. M.
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

A precisely controlled, low range humidity system [PDF]

open access: yes
Development of environmental control system for determining effects of relative humidity and dry heat on inactivation of ...
Garst, D. M., Lindell, K. F.
core   +1 more source

Humidity control by heat reclaim

open access: yesInternational Journal of Energy Research, 2001
The introduction of high-efficiency desiccant rotors with the possibility of being regenerated by low-temperature heat offers new opportunities to the desiccant technique in the field of air conditioning. The use of energy recovered from the condensers of the chillers or from CHP units to obtain humidity control in buildings involves a remarkable fall ...
openaire   +2 more sources

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Autogenous shrinkage of zeolite cement pastes with low water-binder ratio [PDF]

open access: yes, 2015
Self-desiccation is one common phenomenon of high-performance cementitious materials characterized by low water to cementitious material ratio (w/c).
De Schutter, Geert   +3 more
core   +1 more source

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