Results 71 to 80 of about 4,805 (238)

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

Advanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu, Jingqu Chen, Zhixing Lin, Wanjun Xu, Tianzheng Wang, Shiyao Li, Die Yang, Frank Caruso   +7 more
wiley   +1 more source

Re-exploring the relationships of humor styles with dark triad and self-esteem using structural equation modelling [PDF]

Previous relationships between Dark Triad and Humor styles are theoretically difficult to interpret since Dark Triad traits present general and specific sources of variance.
García, Luis F., García, Oscar, Escorial Martín, Sergio, García López, Óscar, Cuevas Esteban, Lara, García Rodríguez, Luis Francisco, Aluja, Antón, Cuevas, Lara, Escorial, Sergio, Balada, Ferrán   +9 more
core   +1 more source

The Relationship of Self Esteem and Humor Styles in First Class Medical Students: A Cross-Sectional Study

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2015
Purpose: Self-esteem and humor styles are significant factors for being a healthy person. The aim of this study was to investigate the relation ship between self-esteem and humor styles in medical students. Material and Methods: Two hundred three medical
Soner Cakmak, Gonca Karakus, Lut Tamam, Ali Tasdemir, Mahmut Onur Karaytug   +4 more
doaj  

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

The relationship between nursıng students\' humor styles and perceived care behaviors [PDF]

Journal of Research Development in Nursing and Midwifery, 2023
Background: Humor creates intimacy between the patient and the nurse, develops a feeling of trust, and positively affects care quality. This study aimed to determine nursing students' humor styles and care behaviors and evaluate the relationship between ...
Burcu Oflaz, Gülcan Kendirkıran
doaj  

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Humor styles of primary school teachers

, 2011
The purpose of this study is to determine humor styles of primary school teachers. With the study, humor styles of teachers and differences in between according to certain variables were determined.
Kürşad Yılmaz, Yahya Altınkurt
core   +1 more source

Transdermal Delivery of an mRNA‐Liposome Vaccine via Dissolving Microneedle to Preserve Vaccine Activity and Enhance Immune Activation

Advanced Science, EarlyView.
An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam, JiWon Ahn, Jiwoo Shin, Nahong Lee, Youjin Lee, Sung min Cho, Paul Kim, Geonwoo Kang, Sang‐Jun Ha, Hyungil Jung   +9 more
wiley   +1 more source

Dark Triad traits & styles of humor

, 2022
The general purpose of this research is to investigate the relationship between Dark Triad traits (machiavellianism, psychopathy, narcissism) and different styles of humor.
Giorgi Chikvaidze
core   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source