Results 81 to 90 of about 468,847 (270)
Advanced Science, EarlyView.This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori +10 more
wiley +1 more source
The Conceptualization, Measurement, and Role of Humor as a Character Strength in Positive Psychology
Europe's Journal of Psychology, 2014 In positive psychology, humor has been identified as one of 24 character strengths considered ubiquitously important for human flourishing. Unlike the other strengths, humor was a late addition to this classification system and its status as a strength ...
Kim R. Edwards, Rod A. Martin
doaj +1 more source
Advanced Science, EarlyView.CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen +19 more
wiley +1 more source
Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila
Advanced Science, EarlyView.While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li +7 more
wiley +1 more source
Advanced Science, EarlyView.Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang +6 more
wiley +1 more source
Dark Triad traits & styles of humor
, 2022 The general purpose of this research is to investigate the relationship between Dark Triad traits (machiavellianism, psychopathy, narcissism) and different styles of humor.
Giorgi Chikvaidze
core +1 more source
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Green Grass Park Picture Description Corpus - Singapore Mandarin Adults
, 2022 This corpus contains audio recordings released by participants under the terms of the Growing Collection. To access this audio, you must agree to the terms of use. This Corpus contains audio recordings and associated information created using the Green
Pan, Lei, Styles, Suzy J
core +1 more source
Sense of Humor, Stable Affect, and Psychological Well-Being
Europe's Journal of Psychology, 2014 A good sense of humor has been implicated as a quality that could contribute to psychological well-being. The mechanisms through which sense of humor might operate include helping to reappraise threats, serving as a character strength, or facilitating ...
Arnie Cann, Chantal Collette
doaj +1 more source
Advanced Science, EarlyView.PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong +14 more
wiley +1 more source