Results 101 to 110 of about 4,805 (238)

Equine models in translational medicine: A comparative approach to human health

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh   +1 more
wiley   +1 more source

Teachers' Metaphorical Perceptions About School Principals' Humor Styles [PDF]

open access: yes, 2018
WOS: 000455272000006The main aim of this study is to determine teachers' perceptions about school principals' humor styles through metaphors. The study, which is the qualitative research, was designed as a basic qualitative research. The working group of
Aduğ, Damla   +2 more
core   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo   +3 more
wiley   +1 more source

The sense of humor in children with grade 1 autism spectrum disorder. Approach to humor styles utilized in humorous tales [PDF]

open access: yes
En la presente investigación pretendemos analizar la creación de humor en menores con trastorno del espectro autista (TEA) de grado 1. En concreto, indagaremos en el empleo de los estilos de humor (Martin, Puhlik-Doris, Larsen, Gray y Wir, 2003) en ...
Merino González, Alicia
core   +1 more source

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li   +11 more
wiley   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello   +20 more
wiley   +1 more source

Variable Effects of Humor Styles on Organizational Outcomes

open access: yes, 2011
The relationship between individual humor styles and several organizational variables was investigated: stress, satisfaction with coworkers, team cooperation, and organizational commitment.
Eric J. Romero, Lucy A. Arendt
core   +1 more source

Seven decades after Hans Asperger’s observations: A comprehensive study of humor in individuals with Autism Spectrum Disorders [PDF]

open access: yes, 2013
The aim of the present study was to better understand humor in individuals with Asperger's syndrome. Therefore, various humor and laughter related phenomena were investigated by means of various standardized humor instruments.
Huber, Oswald   +3 more
core   +1 more source

Choosing One’s Words: Conversational Indirectness and Humor Style in Two Distinct Cultural Groups

open access: yesBehavioral Sciences
We investigated cultural differences in the relationship between conversational indirectness and styles of humor use. Our study compared responses of English first language (L1) users (n = 56) and Korean first language users studying in the US (n = 32 ...
Tanisha Y. Berrios   +2 more
doaj   +1 more source

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