Results 111 to 120 of about 173,621 (252)

Biofilm formation during pneumococcal carriage imprints naturally acquired humoral immunity. [PDF]

PLoS Pathog
Lane JR, Mauser H, Santana-Krimskaya SE, Konda VS, DePass A, Ercoli G, Prokopczuk FI, Mohasin M, D'Mello A, Tettelin H, Brown JS, Reyes LF, Orihuela CJ.   +12 more
europepmc   +2 more sources

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

The Impact of Immunoglobulins on Cardiovascular Diseases and Lipid Profiles in Elderly and Middle‐Aged Chinese Individuals: A 15‐Year Retrospective Study

Journal of Clinical Laboratory Analysis, EarlyView.
In a 15‐year retrospective study of Chinese adults over 45, we explored the links between immunoglobulins, CVDs, and lipid profiles. Temporal increases in IgG and IgA were positively associated with FFAs, offering new insights into humoral immunity and lipid metabolism, suggesting a mechanistic link between humoral immunity and dyslipidemia ...
Ya Li, Li Jiao, Yuan Gao, Xue‐Feng Ni
wiley   +1 more source

Flow Cytometric Lymphocyte Subset Enumeration for Lymphopenia Grading and C‐Reactive Protein‐Defined Inflammation Discrimination

Journal of Clinical Laboratory Analysis, EarlyView.
This study refines conventional lymphopenia grading by establishing optimized T‐cell cutoffs via flow cytometric lymphocyte subset profiling. Additionally, by evaluating individual subset performance (CD4+, CD8+, B, and NK cells), the framework integrates these counts to construct predictive models for infection‐associated inflammation.
Shicheng Li, Tingting Fu, Yang Yang, Yuwei Pu, Wenying Yan, Junjun Zhang   +5 more
wiley   +1 more source

Hunting for an Antigen: Humoral Immunity in Alzheimer's Disease. [PDF]

Cells
Delgado AM, Greer BD, Maul RW, Gearhart PJ.   +3 more
europepmc   +1 more source

Are All “Good” Employees Susceptible to Moral Biases? Exceptional (Versus Intermediate) Moral Character Shapes Resilience to Daily “DIAMONDS” Situations That Trigger Moral Disengagement

Journal of Organizational Behavior, EarlyView.
ABSTRACT The non‐rationalist view of morality holds that all employees—including “good” apples—are liable to do bad because they are susceptible to moral biases in everyday situational encounters. In contrast, the rationalist or trait view suggests that employees with strong moral character should be resilient against moral biases across situations and
Babatunde Ogunfowora, Varun Sharma, Mohammad Khalilinejad, Kimberly Weston Moore   +3 more
wiley   +1 more source

Epigenetic regulation of humoral immunity: molecular mechanisms, diseases and therapeutic targets. [PDF]

Signal Transduct Target Ther
Zhang S, Wang Y, Min X, Wu Y, Liu W.
europepmc   +1 more source

Association between periodontitis and exudative retinal detachment: A population‐based cohort study

Journal of Periodontology, EarlyView.
Abstract Background To investigate whether periodontitis, a common bacterial‐induced inflammatory condition, serves as a risk factor for exudative retinal detachment (ERD), which results from fluid entering the subretinal space due to damage to the retinal pigment epithelium or leaky intraocular vessels, typically associated with inflammatory ...
Earl Fu, Ming‐Ling Tsai, Tsu‐Hsuan Weng, Chi‐Hsiang Chung, Min‐Wen Fu, Wu‐Chien Chien   +5 more
wiley   +1 more source

Non-HLA Antibodies in Kidney Transplantation: Mediators of Allograft Injury or Markers of Dysregulated Humoral Immunity? [PDF]

Med Sci (Basel)
Fouza A, Daoudaki M.
europepmc   +1 more source