Results 121 to 130 of about 233,840 (291)

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham   +11 more
wiley   +1 more source

Humour processes for creative engineering design [PDF]

open access: yes, 2016
Humour has long been associated with creativity, however the link has rarely been applied to engineering design. This paper highlights analogies between humour creation and engineering design, and discusses opportunities to develop new processes and ...
Hatcher, Gillian   +5 more
core  

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu   +7 more
wiley   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

open access: yesAdvanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez   +4 more
wiley   +1 more source

Humour Integrated Language Learning (HILL)

open access: yesThe European Journal of Humour Research
There has been a notable surge in the studies on humour in the language classroom in the past two or even three decades. This burgeoning literature seems to have already entered the threshold of a field of study.
Mohammad Ali Heidari-Shahreza
doaj   +1 more source

Humorous Field - Field to Humour = 幽默地誌 - 地致幽默

open access: yes, 2016
This is an experiment in spatial humour, and this assumption of humour can be applied to any urban space. Since this project starts with Lingnan University’s support of its Artist-in-Residence Program, it would seem appropriate to base the experiment ...
SO, Kwok Kin
core  

Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain

open access: yesAdvanced Materials, EarlyView.
A radiofrequency antenna platform comprising planar and bend configurations is developed, incorporating structurally integrated epsilon‐negative metamaterial unit cells to enhance MRI. These antennas enable high‐resolution in vivo human MRI of the eye, orbit, and occipital brain. Comprehensive validation, including simulations, phantom experiments, SAR,
Nandita Saha   +14 more
wiley   +1 more source

Humour Runs through the Multicoloured Mosaic of Neuropsychotherapy: Scoping Review

open access: yesNeurologijos seminarai
Background. The investigation is devoted to explore the possibilities of humour to treat neuropsychiatric disorders which, in the last decade, have significantly increased. The aim of the study is to describe the growing investigations, in which various
M. Šeduikienė, V. Matonis
doaj   +1 more source

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