Results 121 to 130 of about 47,762 (310)

The comic, not the comedy: effect of joke-origin-induced expectancy on cognitive humour.

open access: yes
Objectives: The present set of experiments examined whether humour expectancy (determined by the joke teller) impacts the humour evaluation of jokes. Design: Across four experiments, participants rated jokes purportedly delivered via celebrity comedians
Mistry, K., Johnson, A.J.
core  

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu   +13 more
wiley   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

open access: yesAdvanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao   +12 more
wiley   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

Advertising and the Organizational Production of Humour

open access: yes, 2014
This chapter discusses humour as it is deliberately produced by organizations through advertising. Using beer advertisements as an example, our aim is to explain the increasing prevalence of advertising-based organizational humour during the period that ...
O'Sullivan, Don   +2 more
core  

Prescribing humour in healthcare : part 1 [PDF]

open access: yes, 2011
The most creative aspect of language is humour I and it is one of the most important topics in the study of communication. The healing power of humour and laughter has been recorded and used throughout history.
Agius, Joseph
core  

An Integrated NLP‐ML Framework for Property Prediction and Design of Steels

open access: yesAdvanced Science, EarlyView.
This study presents a data‐driven framework that uses language‐processing techniques to interpret steel processing descriptions and machine‐learning models to predict mechanical properties. By organising complex process histories into meaningful groups and enabling rapid property forecasts, the work supports faster, more informed steel design through ...
Kiran Devraju   +5 more
wiley   +1 more source

Humour and Learning: A Self-Study of My Practice as an Adult Educator

open access: yes, 2013
This study examined my lived experiences as a frontline practitioner and adult educator in a local nonprofit community organization. Using self-study research methodology, I explored my professional practice as a facilitator of job search skills training
Samuels, Joanna
core  

“I did not actually hear George Washington say that”

open access: yesThe European Journal of Humour Research
The topic of US presidential humour has been investigated in the past, specifically as it was used in presidential debates, press conferences, and at the White House Correspondents’ Dinner.
Moshe Machlev
doaj   +1 more source

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