Results 131 to 140 of about 47,762 (310)

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

open access: yesAdvanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård   +19 more
wiley   +1 more source

L’umorismo nero di Alberto Savinio

open access: yes, 2016
The black humour – privileged by surrealists for its capacity to bring to the surface those psychic contents regarded as taboo, especially those related to death, disease, violence and sexuality (it was Breton himself who coined the expression humour ...
Bulumete, Miruna
core  

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

open access: yesAdvanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen   +14 more
wiley   +1 more source

Η σχέση του “Καραγκιόζη” με το νεοελληνικό γέλιο

open access: yes, 2015
Κατά καιρούς, έχει αμφισβητηθεί η άποψη ότι ο Καραγκιόζης και οι ήρωες του νεοελληνικού Θεάτρου Σκιών ανήκουν στους λεγόμενους «πατέρες» της νεοελληνικής σάτιρας.
Agrafiotis, Thomas
core  

The language of humour: the humour of language irony and humour in interpersonal verbal encounters

open access: yesBucharest Working Papers in Linguistics, 2008
In this paper the problem of verbal humour and irony is approached from a sociolinguistic perspective, starting from the Semantic Script Theory of Humour (Raskin 1985), which establishes that all humour involves a semantic-pragmatic process. Humour should be understood and appreciated shared socio-cultural knowledge; a common code should exist between ...
openaire   +1 more source

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

open access: yesAdvanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan   +13 more
wiley   +1 more source

Subtext as humour: Grammatical ‘hidden meaning’ as part of pun and metaphor in English

open access: yes, 2017
Corpus-derived subtext is a new development in Contextual Prosodic Theory (Louw 2010a), which this paper employs, among other tools provided by CPT, in the attempt to give corpus-attested definitions of pun and metaphor.
Milojkovic, Marija
core  

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

open access: yesAdvanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim   +4 more
wiley   +1 more source

Humour in Popularization: Analysis of humour-related laughter in TED talks

open access: yes, 2013
This paper investigates the role of humour in TED talks, which are popularising speeches aiming at knowledge dissemination. Through the analysis of humour used in Eugene Cordero’s 2012 talk ‘Improv Everywhere: A TED speaker’s worst nightmare’, Sebastian ...
Scotto di Carlo, G.
core  

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