Results 111 to 120 of about 389,017 (260)
Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila
Advanced Science, EarlyView.While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li +7 more
wiley +1 more source
Humour styles as mediators between self-esteem and loneliness [PDF]
, 2019 : Self-esteem may be viewed as a gauge from which people measure their social acceptance levels; it arises out of a need to protect the individual from, especially, social factors.
Delaney, Heather G.
core
Advanced Science, EarlyView.Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang +6 more
wiley +1 more source
The relationship between humour styles and the Theory of Mind
, 2022 Humour is a complex phenomenon defined as a cognitive-affective style of dealing with adverse situations through amusement, which elicits a positive cognitive and affective response in people. In this study, three differ-ent theories are described. The two theories that consider Theory of Mind and humour together, the Mind Reading Hypothesis (Howe ...
openaire +2 more sources
Frontiers in Political ScienceThis paper examines a 90-min rally speech delivered by Trump in Michigan in 2025 to commemorate the first 100 days of his second presidency. Drawing on Lewin et al.’s leadership styles typology alongside Archer’s concept of Reality Paradigms, it adopts a
Dawn Archer
doaj +1 more source
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Advanced Science, EarlyView.PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong +14 more
wiley +1 more source
The Effect of Humour Style on Premenstrual Syndrome: A Cross-Sectional Study
Journal of NursologyObjective: This study aimed to determine the effect of humour style on premenstrual syndrome (PMS). Methods: The population of the descriptive and cross-sectional study consisted of 7,573 female students attending the university. The layered sampling method was used for sample selection, and the research was completed with 327 students.
Sümeyye Buldu, Funda Tosun Güleroğlu
openaire +1 more source
The Irish stew according to Jerome K. Jerome
The European Journal of Humour ResearchIn 1889, Jerome K. Jerome published Three Men in a Boat, a special kind of travelogue. As the gluttonous heroes make food their main preoccupation, the modest excursion on the Thames quickly turns into a heroic-comic quest.
Hélène Dubail
doaj +1 more source
Advanced Science, EarlyView.Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh +22 more
wiley +1 more source