ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
Systematic Literature Review: Computational Approaches for Humour Style Classification
Understanding various humour styles is essential for comprehending the multifaceted nature of humour and its impact on fields such as psychology and artificial intelligence. This understanding has revealed that humour, depending on the style employed, can either have therapeutic or detrimental effects on an individual's health and relationships ...
Kenneth, Mary Ogbuka +2 more
openaire +1 more source
ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu +12 more
wiley +1 more source
Preservice teachers' attitudes toward pedagogical humour: the role of physical activity, sociodemographic factors, and academic discipline. [PDF]
Çakır Z +8 more
europepmc +1 more source
Distinct Biotypes of Visual Perception in Major Depressive Disorder
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai +13 more
wiley +1 more source
Honour across borders: How cultural norms shape prejudice confrontation in migration contexts. [PDF]
Uysal MS, Kessler T, Uskul AK.
europepmc +1 more source
Neuromodulator Dynamics Underlying Associative Learning in the Ventral Striatum's Olfactory Tubercle
Using fiber photometry and genetically encoded sensors, the dynamic release patterns of four neuromodulators in the olfactory tubercle (OT)—a brain region overlapping with the olfactory cortex and ventral striatum—were systematically monitored in response to external rewards and distinct reward‐associated learning processes.
Maojun Hong +7 more
wiley +1 more source
Self-efficacy and Communication in Health Personnel After Simulation Training in Cardiopulmonary Resuscitation: A Quasi-experimental Study. [PDF]
Pérez-Fuentes MDC +5 more
europepmc +1 more source
Ising machines are emerging as specialized hardware solvers for computationally hard optimization problems. This review examines five major platforms—digital CMOS, analog CMOS, emerging devices, coherent optics, and quantum systems—highlighting physics‐rooted advantages and shared bottlenecks in scalability and connectivity.
Hyunjun Lee, Joon Pyo Kim, Sanghyeon Kim
wiley +1 more source
Coping strategies, hierarchy of values, perceived stress and satisfaction with life in the group of uniformed personnel treated in mental health clinic. [PDF]
Curyło M +27 more
europepmc +1 more source

