Results 61 to 70 of about 831,202 (328)

Toward Advancement of Fabrication Techniques of Neuromorphic Computing Devices Based on 2D Materials

open access: yesAdvanced Materials Technologies, EarlyView.
This review highlights emerging fabrication techniques of 2D material‐based neuromorphic devices, emphasizing proximity vapor transfer for bioinspired optoelectronic applications. Abstract The growing necessity for power‐efficient and cognitive computation mechanisms has driven progress in neuromorphic computing which seeks to imitate the synaptic ...
Shubham Umeshkumar Gupta   +7 more
wiley   +1 more source

Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice

open access: yesAdvanced Science, EarlyView.
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang   +16 more
wiley   +1 more source

The Paleolithic in Hungary [PDF]

open access: yes, 2018
This is a postprint version of a chapter in the Encyclopedia of Global Archaeology second edition edited by C. Smith and published by Springer Nature Switzerland AG in 2018.
openaire   +2 more sources

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

open access: yesAdvanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng   +7 more
wiley   +1 more source

The Public Opinion about the Death Penalty in Hungary and Worldwide: What Do Polls on Capital Punishment Show?

open access: yesKrytyka Prawa, 2020
A number of representative polls have been conducted on the death penalty in recent decades. There were some surveys whose authors were interested not only in the percentage of supporters and opponents of the death penalty, but also in whether this rate ...
Zoltan Toth
doaj   +1 more source

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
In SETD2‐mutant ccRCC, the original LEDGF recognition of the H3K36me3 regulatory axis no longer exists. LEDGF interacts with CARM1‐dependent H3R17me2a regulating the transcription of key enzymes in the de novo synthesis pathway. The abnormally elevated LEDGF leads to the accumulation of purine nucleotides in SETD2‐mutant ccRCC, thereby satisfying the ...
Yuwei Zhang   +11 more
wiley   +1 more source

Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition

open access: yesAdvanced Science, EarlyView.
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu   +12 more
wiley   +1 more source

Sustainability and Control Issues of the Financial Management of Local Governments – Through Hungary’s Example

open access: yesVisegrad Journal on Bioeconomy and Sustainable Development, 2019
The rules and control mechanisms pertaining to the financial management of local governments enhance the sustainability of their budgets, that is, they have an operational risk mitigating effect.
Lentner Csaba
doaj   +1 more source

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang   +15 more
wiley   +1 more source

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