Results 61 to 70 of about 1,917 (165)

Tks4‐Targeted Gene Therapy Inhibited White Adipocyte Hypertrophy in Mice

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Tks4 knockout or knockdown by AAV mediated shRNA both successfully restricted adipocyte hypertrophy in high fat diet. The reduction of TAG was validated by biochemistry and lipidomics analyses. This study suggested a potential of Tks4 targeted therapy in obesity intervention. ABSTRACT Obesity is one of the most prevalent public health issues worldwide,
Meng Tian, Jingwen Deng, Yuzhu Hong, Ruitong Liu, Shengnan Li, Xiaoxiao He   +5 more
wiley   +1 more source

Microfabricated Neural Biosensors for Detection of Neurotransmitters, Biomarkers, and Small Molecules: Emerging Trends on Self‐Sustained Systems and Energy Harvesting

Advanced Sensor Research, Volume 5, Issue 1, January 2026.
This paper reviews the state of the art and recent developments in thin‐film biosensors for the detection of neurotransmitters, small molecules, and biomarkers within flexible, implantable bioelectronic systems. It covers the main sensing modalities, including electrochemical, plasmonic, acoustic, and magnetic, alongside their materials, transduction ...
Massimo Mariello
wiley   +1 more source

Severe hypercalcemia and a pelvic brown tumor in an adolescent with primary hyperparathyroidism: a case report

BMC Pediatrics, 2020
Background Primary hyperparathyroidism may present in a myriad of manners, varying from an incidental asymptomatic biochemical finding to gastrointestinal, psychiatric, renal, and bone manifestations. While hyperparathyroidism remains a rare diagnosis in
O. Legault, M. Inman, N. Moolman, S. Wiebe, A. Poulin, M. A. Nour   +5 more
doaj   +1 more source

Developmental Impact of Maternal Immune Activation on the Fetal Immune System and Lung

European Journal of Immunology, Volume 56, Issue 1, January 2026.
Maternal immune activation triggers elevated cytokines (IL‐6 and IL‐17A), disrupting fetal immune system development. This not only alters hematopoietic stem cell balance but also leads to ILC2 hyperactivation in the lung, which could potentially affect susceptibility to allergic diseases in the offspring.
Walaa Jradi, Kira Duhm, Clarissa Prazeres da Costa   +2 more
wiley   +1 more source

Mitigation of Metabolic Diseases Through Personalized Nutrition: A Critical In‐Depth Review

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
The main objective of this review is to explore the impact of variation within the microbiome and among genes on nutrient metabolism and argue in favor of successful evidence of individualized dietary intervention for cardiovascular disease, diabetes, and obesity.
Muhammad Tayyab Arshad, M. K. M. Ali, Farhang Hameed Awlqadr, Sammra Maqsood, Ali Ikram, Md. Sakhawot Hossain, Muhammed Adem Abdullahi, M. M. Rashed   +7 more
wiley   +1 more source

Advances and challenges in point‐of‐care testing for pathogenic bacteria in battlefield injuries

Interdisciplinary Medicine, Volume 4, Issue 1, January 2026.
This review explores trauma‐associated bacterial species, summarizes these biosensor advancements, addresses fabrication challenges, outlines future directions, and aims to guide POCT biosensor development for combat/trauma care bacterial detection.
Junjie Fan, Shuai Liu, Dan Luo, Hengjun Zhang, Xianling Dai, Hanqing Xu, Man Shen, Yingchun Huang, Yupeng Long, Ming Chen, Qiaofeng Li, Jing Bao   +11 more
wiley   +1 more source

[Hungry bone syndrome related to hyperthyroidism].

Anales de medicina interna (Madrid, Spain : 1984), 2006
Hungry bone syndrome is a common clinical entity which is accompanying of hypocalcemia, hypomagnesemia, and hipophosphatemia, results from an increase in bone formation. It is related to a pathological scenario which causes an imbalance between osteoclast-mediated bone resorption and osteoblast-mediates bone formation, favouring the latter. Its classic
M D, Moure Rodríguez, M, Luque-Ramírez, G, López Gallardo, M, López Iglesias, A, Gómez-Pan   +4 more
openaire   +1 more source

Hungry bone syndrome: biochemical and clinical risk factors

Diagnostyka Laboratoryjna, 2019
Primary hyperparathyroidismremains the first cause of hypercalcaemia. Parathyroid surgery is the most efficient treatment of primary hyperparathyroidism, however surgery entails risk of development of a Hungry Bone Syndrome (HBS) – rapid, profound, and prolonged hypocalcaemia.
Ewa Kozłowska, Olga Ciepiela
openaire   +1 more source

Outcomes of renal hyperparathyroidism following parathyroidectomy in kidney replacement therapy patients at a tertiary centre in South Africa: A retrospective cohort study

Journal of the Colleges of Medicine of South Africa
Background: Renal hyperparathyroidism is a frequent complication among patients with kidney failure. Data on outcomes following parathyroidectomy in patients undergoing kidney replacement therapy (KRT) remain limited in South Africa (SA).
Tholakele Sabela, Nontembiso Mhlana, Wilhelmina Conradie, Mogamat-Yazied Chothia   +3 more
doaj   +1 more source

Recurrent severe hypocalcemia following chemotherapy regimen changes in advanced breast cancer: two case reports

Journal of Medical Case Reports
Background As an oncologic emergency related to abnormalities in calcium metabolism, hypercalcemia associated with paraneoplastic syndrome and bone metastases is well known. Meanwhile, the incidence of hypocalcemia is low, except in cases associated with
Yurina Yanase, Hiroko Bando, Riko Sato, Tomohei Matsuo, Aya Ueda, Mai Okazaki, Sachie Hashimoto, Akiko Iguchi-Manaka, Hisato Hara   +8 more
doaj   +1 more source