Results 71 to 80 of about 237,393 (226)

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

open access: yesAdvanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu   +7 more
wiley   +1 more source

Ancient oral microbiomes support gradual Neolithic dietary shifts towards agriculture

open access: yesNature Communications, 2022
Here, the authors compare 76 dental calculus oral microbiomes from Palaeolithic hunter-gatherers with Neolithic and Copper Age farmers living in the same region of Italy.
Andrea Quagliariello   +21 more
doaj   +1 more source

Pacifying Hunter-Gatherers [PDF]

open access: yes, 2019
There is a well-entrenched schism on the frequency (how often), intensity (deaths per 100,000/year), and evolutionary significance of warfare among hunter-gatherers compared with large-scale societies.
Hames, Raymond B
core  

MOF‐Derived Cu‐TiO2/Alginate Micromotors for Buoyancy‐Regulated 3D Motion

open access: yesAdvanced Science, EarlyView.
In this work, cyanobacteria‐inspired sodium alginate (SA)/Cu‐TiO2/Fe3O4 hydrogel micromotors generate and encapsulate O2 microvesicles upon light irradiation, enabling buoyancy‐mediated Z‐axis upward migration and surface enrichment at the light‐exposed water‐air surface.
Wei Zou   +7 more
wiley   +1 more source

Archaeologists, Hunter-Gatherers of Digital Data

open access: yesInternet Archaeology
The rapid advancement of digital technologies has paved the way for a revolution in archaeological documentation. Since digital cameras, tablets, portable printers, drones, and other technical gadgets have become readily available and easily replaceable,
Rafko Urankar   +2 more
doaj   +1 more source

Late Pleistocene human genome suggests a local origin for the first farmers of central Anatolia

open access: yesNature Communications, 2019
Central Anatolia harbored some of the earliest farming societies outside the Fertile Crescent of the Near East. Here, the authors report and analyze genome-wide data from a 15,000-year-old Anatolian hunter-gatherer and from seven Anatolian and Levantine ...
Michal Feldman   +17 more
doaj   +1 more source

Nutritional Status, Activity Pattern, and Dietary Intake among the Baka Hunter-gatherers in the Village Camps in Cameroon [PDF]

open access: yes, 2000
The nutritional status of 75 male and 73female pygmy hunter-gatheres were surveyed as well as the daily physical activity, energy and intake of major nutrients, and total energy expenditure were examined for two married couples of the Baka hunter ...
KAWAMURA, Kyohei   +2 more
core   +1 more source

Nonlinear Quantum Effects Drive Grotthuss Proton Conduction in Structured Electrolytes Based on Deep Eutectic Solvents

open access: yesAdvanced Science, EarlyView.
We demonstrate that the inverse relationship between viscosity and conductivity in structured electrolytes can be circumvented by leveraging their hydrogen bonding networks for Grotthuss proton transport. Using a mixture of imidazole and levulinic acid, we show that the existence of extended hydrogen‐bonded chains that can rapidly reorient result in ...
Benworth B. Hansen   +15 more
wiley   +1 more source

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng   +14 more
wiley   +1 more source

Saharan Hunter-Gatherers. Specialization and diversification in Holocene southwestern Libya

open access: yes, 2023
The book offers a fresh interpretation of the development of Early Holocene hunter-gatherers of Central Sahara. Focussed on southwestern Libya, the book examines the cultural trajectories of specialized and diversified hunter gatherers of the Tadrart ...
Di Lernia, Savino
core  

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