Results 91 to 100 of about 802,919 (366)

A hunter-gatherer-farmer population model: Lie symmetries, exact solutions and their interpretation

, 2014
The Lie symmetry classification of the known three-component reaction-diffusion system modelling the spread of an initially localized population of farmers into a region occupied by hunter-gatherers is derived.
Anna Niemcunowicz-Janica (457677), Anna Szpakowicz (457672), Ewa Waszkiewicz (457674), Grzegorz Opolski (117217), Karol Adam Kaminski (457681), Marek Kiliszek (117207), Maria Franaszczyk (236545), Małgorzata Skawronska (457676), Rafal Ploski (348433), Sławomir Dobrzycki (457679), Witold Pepinski (457673), Włodzimierz Jerzy Musial (457680)   +11 more
core   +4 more sources

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

The first vs. second stage of neolithisation in Polish territories (to say nothing of the third?)

Documenta Praehistorica, 2019
The origins of the Neolithic in Polish territories are associated with migrations of groups of the Linear Band Pottery culture (LBK) after the mid-6th millennium BC.
Marek Nowak
doaj   +1 more source

Uncoupling Metastasis and Epithelial‐to‐Mesenchymal Transition in sgP19/kRAS‐Driven Spontaneous Metastatic Liver Tumor Model

Advanced Science, EarlyView.
The article first reported that a murine mixed typical intrahepatic cholangiocarcinoma (iCCA)/sarcomatoid iCCA liver tumor model with 100% incidence of spontaneous extrahepatic metastasis and confirmed the occurrence of in mouse iCCA. Most importantly, EMT induced by the TGF‐β/ZEB1 axis does not influence tumor development or distant metastasis in this
Jingwen Wang, Zijing Xu, Lei Xu, Lishan Wang, Jiahao Geng, Xue Wang, Meng Xu, Daphne Superville, Melissa Reeves, Matthias Evert, Diego F. Calvisi, Xin Chen, Xinhua Song   +12 more
wiley   +1 more source

Epipalaeolithic animal tending to Neolithic herding at Abu Hureyra, Syria (12,800-7,800 calBP): Deciphering dung spherulites.

PLoS ONE, 2022
Excavations at Abu Hureyra, Syria, during the 1970s exposed a long sequence of occupation spanning the transition from hunting-and-gathering to agriculture. Dung spherulites preserved within curated flotation samples from Epipalaeolithic (ca.
Alexia Smith, Amy Oechsner, Peter Rowley-Conwy, Andrew M T Moore   +3 more
doaj   +1 more source

Ancient human genomes suggest three ancestral populations for present-day Europeans [PDF]

, 2014
We sequenced the genomes of a 7,000-year-old farmer from Germany and eight 8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes¹-₄ with 2,345 contemporary humans to show that most present-day Europeans ...
Churnosov, M. I., Lazaridis, I., Mittnik, A., Patterson, N., Renaud, G.   +4 more
core  

The Genetic Structure and History of Africans and African Americans. [PDF]

, 2009
Africa is the source of all modern humans, but characterization of genetic variation and of relationships among populations across the continent has been enigmatic. We studied 121 African populations, four African American populations, and 60 non-African
A. A. Awomoyi, A. Froment, A. Ranciaro, A. T. Juma, Batini, Behar, Bereir, C. Ehret, C. Wambebe, Campbell, Cann, Cerny, Chen, Coia, Destro-Bisol, F. A. Reed, F. R. Friedlaender, Forster, Forster, Friedlaender, G. Lema, G. S. Pretorius, H. Mortensen, Hassan, J. B. Hirbo, J. H. Moore, J. L. Weber, J.-M. Bodo, Jakobsson, K. Powell, Li, Lind, M. A. Thera, M. Ibrahim, M. J. Kotze, M. W. Smith, O. Doumbo, Parra, Parra, Patin, Patterson, Pritchard, Pritchard, Reed, Reynolds, Rosenberg, Rosenberg, Rosenberg, S. A. Omar, S. A. Tishkoff, S. M. Williams, Salas, Scozzari, Semino, Sirugo, Smith, T. B. Nyambo, Tishkoff, Tishkoff, Verdu, Wang, Wood   +61 more
core   +1 more source

Physical activity patterns and biomarkers of cardiovascular disease risk in hunter‐gatherers

American Journal of Human Biology, 2017
Time spent in moderate‐to‐vigorous physical activity (MVPA) is a strong predictor of cardiovascular health, yet few humans living in industrialized societies meet current recommendations (150 min/week).
D. Raichlen, H. Pontzer, J. Harris, A. Mabulla, F. Marlowe, J. Josh Snodgrass, G. Eick, J. Colette Berbesque, A. Sancilio, B. Wood   +9 more
semanticscholar   +1 more source

Modern and Ancient Genomes Reveal Neolithic Paternal Expansions of Millet and Rice Farmers and Demic Diffusion from China into Mainland Southeast Asia

Advanced Science, EarlyView.
This study clarifies the genetic patterns of paternal lineages across East Asia and Mainland Southeast Asia. Han populations are relatively homogeneous, whereas southern ethnolinguistic minorities display regional structures. Shared Y‐chromosome lineages indicate Neolithic expansions and extensive north‐south gene flow, supporting demic diffusion ...
Yunhui Liu, Lintao Luo, Yutong Jiang, Minzhu Zhao, Ting Yang, Zhiyong Wang, Lisiteng Luo, Yuhang Feng, Zihao Zhu, Yuzhu Wang, Limei Zhang, Bofeng Zhu, Chao Liu, Renkuan Tang, Mengge Wang, Guanglin He   +15 more
wiley   +1 more source

Historical Linguistics and Philippine Hunter-Gatherers [PDF]

, 2007
This paper addresses several topics with reference to Philippine hunter-gatherer groups that are relevant to an understanding of their relationships with non-hunter-gatherer groups and their significance for historical linguistics.
Reid, Lawrence A.
core