Results 71 to 80 of about 84,353 (267)
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Illegal hunting of wildlife is a major issue in today’s society, particularly in tropical ecosystems. In this study, a total of 114 local residents from eight villages located in four wards adjacent to the northern Gonarezhou National Park, south-eastern
Gandiwa, E.
core
The veterinary aspects of public administration in the trade of hunting and fishing products in Galicia of the 19th and the beginning of the 20th centuries are considered.
Ihor Drobot, Oleg Protsiv
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Polygamy in the Marsh Harrier, Circus aeruginosus: Individual Variation in Hunting Performance and Number of Mates [PDF]
1. Theories postulating that sexual task differentiation may lead to polygamy such that the sex investing the least effort in raising the offspring, engages in simultaneous matings, contrast with polygyny in raptors where the male provides most of the ...
Altenburg, Wibe, +7 more
core +1 more source
It is 25 years since Tim Hunt discovered cyclin, the oscillating protein that drives activation of cyclin-dependent kinases and entry into mitosis (Evans et al., 1983).
openaire +3 more sources
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Demand for Wildlife Hunting in British Columbia [PDF]
We present estimates of the demand for hunting licenses by residents and non residents in British Columbia for the period 1971–2000. We obtain estimates of both short-run and long-run price elasticities and discuss their revenue implications for future ...
G. Cornelis van Kooten +2 more
core
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source

