Results 51 to 60 of about 200,168 (344)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

On the permissible standards for the use (shooting, catching) of certain species of game animals

Novitates Theriologicae
The author presents his own views and experience on the organisation of state control over hunting management in Ukraine. The basis of such statements is the experience of the Mykolaiv Regional Forestry and Hunting Administration in implementing measures
Gennadiy Boyko
doaj   +1 more source

Co-management of the migratory caribou herds in northern Québec: The perspective of the Hunting, Fishing and Trapping Coordinating Committee

Rangifer, 2012
Aboriginal people have a long relationship with caribou, and caribou - especially the large migratory herds- cross aboriginal territories and jurisdictional boundaries.
Nicole Gougeon
doaj   +1 more source

The first case of golden jackal (Сanis aureus Linnaeus, 1758) appearance in Penza region

Известия высших учебных заведений. Поволжский регион: Естественные науки, 2022
Background. In recent decades, the golden jackal (Canis aureus) has spread northward, including in the Volga region. Finding a species belonging to a desert faunal complex far from the main range is important for the study of biological diversity and ...
O.A. Ermakov, D.V. Salagin, N.V. Bystrakova   +2 more
doaj   +1 more source

Tournaments and hunting

, 2021
This chapter considers tournaments and hunting as aspects of early modern court culture. It briefly sets out the cultural context of both quasi-martial sports among elite men (and women) as ways of expressing status and looks at their importance for the princes who hosted them.
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The Hunt for Axions [PDF]

Proceedings of XVI International Workshop on Neutrino Telescopes — PoS(NEUTEL2015), 2016
Many theoretically well-motivated extensions of the Standard Model of particle physics predict the existence of the axion and further ultralight axion-like particles. They may constitute the mysterious dark matter in the universe and solve some puzzles in stellar and high-energy astrophysics. There are new, relatively small experiments around the globe,
openaire   +4 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source