Results 261 to 270 of about 49,474 (299)

Roscovitine, a CDK Inhibitor, Reduced Neuronal Toxicity of mHTT by Targeting HTT Phosphorylation at S1181 and S1201 In Vitro. [PDF]

Int J Mol Sci
Liu H, McCollum A, Krishnaprakash A, Ouyang Y, Shi T, Ratovitski T, Jiang M, Duan W, Ross CA, Jin J.   +9 more
europepmc   +1 more source

Huntingtin and Huntingtin-Associated Protein 1 Influence Neuronal Calcium Signaling Mediated by Inositol-(1,4,5) Triphosphate Receptor Type 1

, 2003
Tie-Shan Tang, Huiping Tu, Matthew T.V. Chan, Anton Maximov, Zhennan Wang, Cheryl L. Wellington, Michael R. Hayden, Ilya Bezprozvanny   +7 more
openalex   +1 more source

Advances in Autophagy-Lysosomal Pathway and Neurodegeneration via Brain-Gut Axis. [PDF]

Biomedicines
Yao P, Han H.
europepmc   +1 more source

Neuroanatomical mapping of huntingtin-associated protein 1 across the rostral and caudal clusters of mouse raphe nuclei and its immunohistochemical relationships with serotonin. [PDF]

Front Neuroanat
Afrin M, Islam MN, Meher MM, Jahan MR, Nozaki K, Masumoto KH, Yanai A, Shinoda K.   +7 more
europepmc   +1 more source

Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington's disease. [PDF]

Neurobiol Dis
Xu H, Ajayan A, Langen R, Chen J.
europepmc   +1 more source

Deuterium trafficking, mitochondrial dysfunction, copper homeostasis, and neurodegenerative disease. [PDF]

Front Mol Biosci
Seneff S, Kyriakopoulos AM.
europepmc   +1 more source

Leucine 7 is a key residue for mutant huntingtin-induced mitochondrial pathology and neurotoxicity in Huntington's disease. [PDF]

J Biol Chem
Zhang S, Wang S, Yang Z, Li Y, Li J, Chen X, Yao H, Zheng Z, Guo X.   +8 more
europepmc   +1 more source

Targeting cGAS-STING signaling: a potential therapeutic approach for the management of Huntington's disease. [PDF]

EXCLI J
Kumar V, Kumar P.
europepmc   +1 more source

Dopamine Receptor D3 Induces Transient, mTORC1-Dependent Autophagy That Becomes Persistent, AMPK-Mediated, and Neuroprotective in Experimental Models of Huntington's Disease. [PDF]

Cells
Luis-Ravelo D, Fumagallo-Reading F, Febles-Casquero A, Lopez-Fernandez J, Marcellino DJ, Gonzalez-Hernandez T.   +5 more
europepmc   +1 more source

In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington's Disease. [PDF]

Pharmaceutics
Morales LC, Modi L, Abbasi Dezfouli S, Rajendran AP, Kc R, Kadam V, Sipione S, Uludağ H.   +7 more
europepmc   +1 more source