Results 241 to 250 of about 36,080 (282)

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

Brain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu, Biniam Moges Eskeziyaw   +1 more
wiley   +1 more source

Increased Activity-Dependent Bulk Endocytosis in Huntington's Disease Results From Huntingtin Haploinsufficiency. [PDF]

J Neurochem
Tan HCG, McAdam RL, Morton A, Cousin MA, Smillie KJ.   +4 more
europepmc   +1 more source

Along-Tract Diffusion Alterations in the Dentato-Rubro-Thalamic Tract Correlate With Motor and Cognitive Decline in Huntington's Disease. [PDF]

Hum Brain Mapp
Wang Z, Solomon A, Lupo JM, Yao J.
europepmc   +1 more source

Acute Presentation of Nonpuerperal Uterine Inversion Following a Diagnosis of Uterine Carcinosarcoma: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Nonpuerperal uterine inversion (NPUI) due to endometrial carcinosarcoma can present in an acute manner with life‐threatening complications. The rare presentation of uterine inversion outside of the puerperium caused by a malignant etiology, which was further complicated by the urgent need for intervention, makes this case crucial in ...
Aman Kaur More, Sarah Louise Smyth, Ana Sofia Cerdeira, Hooman Soleymani majd   +3 more
wiley   +1 more source

Population Pharmacokinetic and Exposure-Efficacy Analyses of Valbenazine in Patients with Huntington's Disease: Supporting Dose Selection for Chorea Management. [PDF]

J Clin Pharmacol
Nguyen HQ, Crass RL, Chapel S, Kuan HS, Loewen G, Brar S.   +5 more
europepmc   +1 more source

Proteomic Analysis of Regulated Dendritic Cell Endosomes Reveals Dynamic Adaptation to Antigen Uptake and Cross‐Presentation

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Alice Senni, Louise Grumbach, Sara Ceccacci, Mathieu Frechin, Nicolas Goudin, Ida Chiara Guerrera, Barbara Bertocci, Peter van Endert   +7 more
wiley   +1 more source

Apathy and Impulsivity Co-Occur in Huntington's Disease. [PDF]

Brain Behav
Morris LA, Horne KL, Paermentier L, Buchanan CM, MacAskill M, Myall D, Husain M, Roxburgh R, Anderson T, Heron CL.   +9 more
europepmc   +1 more source

Ginsenoside Rg1 as a Multifunctional Therapeutic Agent: Pharmacological Properties, Molecular Mechanisms and Clinical Perspectives in Complementary Medicine

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés, Enrique Lima, Lorena Duarte‐Peña, Sheila I. Peña‐Corona, Zainab M. Almarhoon, Rajesh Kaverikana, Shivaprasad Shetty Mangalpady, Vinayaka Babu Shet, Nikshitha Manjeshwar, Javad Sharifi‐Rad, Jen‐Tsung Chen, Gerardo Leyva‐Gómez, William N. Setzer, Daniela Calina   +13 more
wiley   +1 more source

Anosognosia and avoidant coping do not impact work in early Huntington's disease. [PDF]

J Huntingtons Dis
van der Zwaan KF, Roos RA, de Bot ST.
europepmc   +1 more source