Antioxidant, Anti-Inflammatory, and Chemical Composition Analysis of In Vitro Huperzia serrata Thallus and Wild Huperzia serrata [PDF]
Huperzine A is a preferred treatment option for Alzheimer’s disease. Huperzia serrata (Thunb. ex Murray) Trev. (H. serrata) has garnered significant attention for its ability to produce Huperzine A (HupA). However, natural populations of wild H. serrata (
Yongchun Huang +7 more
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Evaluation of genetic diversity and structure of the endangered medicinal plant genus Huperzia (Lycopodiaceae) in China based on EST–SSR markers [PDF]
Huperzia serrata is an endangered perennial medicinal lycophyte, primarily distributed across most regions of China, eastern and southern Asia, Oceania, and the Americas.
Muzi Li +12 more
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The complete chloroplast genome of an Arctic lycophyte, Huperzia arctica (Tolm.) Sipliv. 1973 (Lycopodiaceae) [PDF]
Huperzia arctica (Tolm.) Sipliv. 1973 is a lycophyte species belonging to the Lycopodiaceae family, which is widely distributed in the Arctic region of Svalbard, Norway.
Youngsim Hwang +3 more
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Lecanicillium aphanocladii: a biocontrol agent against insect pests and phytopathogens. [PDF]
Recent research findings on the biocontrol potential of Lecanicillium aphanocladii fungus against insect‐pests and plant diseases were highlighted. This review indicates that several L. aphanocladii strains show great potential to be developed as multipurpose biocontrol agents active against several insect‐pests, plant diseases and plant parasitic ...
Liu Q, Johnson R, Adusei-Fosu K.
europepmc +2 more sources
Natural Chiral Scaffolds in Alzheimer's Disease: Therapeutic Potential, Mechanism, and Clinical Aspects. [PDF]
Alzheimer′s disease (AD) is a multifactorial neurodegenerative disorder characterized by progressive cognitive impairment, amyloid‐β deposition, tau pathology, oxidative stress, neuroinflammation, and dysfunction of synapses. Current therapeutic options are largely symptomatic and lack disease‐modifying efficacy.
Singh A, Sahu SK, Sah AK.
europepmc +2 more sources
Loss of Pathogenicity and Evidence of Horizontal Gene Transfer in Colletotrichum gloeosporioides From a Medicinal Plant. [PDF]
A Colletotrichum gloeosporioides strain from Huperzia serrata lacks key pathogenicity genes CgDN3 and cap20 and has fewer pelB, pnl and pg genes. pksIII, for synthesis of huperzine A, was probably acquired by the host plant from the fungus. ABSTRACT Colletotrichum gloeosporioides is a major agricultural pathogen of crops that has also been identified ...
Yue X +17 more
europepmc +2 more sources
Rhizospheric soil alter extracellular vesicles in the roots of Huperzia serrata and their carried miRNA [PDF]
IntroductionAs a valuable traditional medicinal plant, it is unclear whether the roots of Huperzia serrata produce extracellular vesicles (EVs), or whether the addition of rhizospheric soil influences the characterization of EVs and the microRNAs (miRNAs)
Na Li +6 more
doaj +2 more sources
Combined transcriptome and widely targeted metabolome analysis reveals the potential mechanism of HupA biosynthesis and antioxidant activity in Huperzia serrata [PDF]
IntroductionHuperzia serrata is a traditional Chinese herb that has gained much attention for its production of Huperzine A (HupA). HupA has shown promise on treating Alzheimer's disease (AD).
Hao Wu +6 more
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Anti-neuroinflammatory effects of alkaloid-enriched extract from Huperzia serrata on lipopolysaccharide-stimulated BV-2 microglial cells [PDF]
Context Alkaloid-enriched extract of Huperzia serrata (Thunb.) Trevis (Lycopodiaceae) (HsAE) can potentially be used to manage neuronal disorders.Objective This study determines the anti-neuroinflammatory effects of HsAE on lipopolysaccharide (LPS ...
Thu Kim Dang +8 more
doaj +2 more sources
Huperzia crassifolia (Lycopodiaceae), a new species from China based on morphological characters and molecular evidence [PDF]
A new species of the firmoss from China, Huperzia crassifolia sp. nov., is described and illustrated based on morphological characters and molecular evidence. The new species resembles species associated with the H.
Zhi-You Guo +6 more
doaj +4 more sources

