Results 111 to 120 of about 5,858 (232)

Therapeutic Promises of Bioactive Linarin, a Glycosylated Flavonoid: A Comprehensive Review With Mechanistic Insight

open access: yesJournal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Linarin, a flavonoid glycoside found in the Asteraceae, Lamiaceae, and Scrophulariaceae families, shows diverse therapeutic benefits in laboratory studies. This study aims to evaluate the pharmacological effects of linarin through clinical and preclinical experiments, investigating its mechanisms against different diseases.
Faysal Mollah   +9 more
wiley   +1 more source

toxines et signalisation

open access: yes, 2009
Collection Rencontres en toxinologie ISSN: 1760-6004 ; http://sfet.asso.fr/images/stories/SFET/pdf/EBook-RT17-2009-signets.pdfInternational ...
Benoit, Evelyne   +3 more
core  

Assessment of enzyme inhibition : a review with examples from the development of monoamine oxidase and cholinesterase inhibitory drugs [PDF]

open access: yes, 2017
Both authors are grateful for the collaborations on multi-target drugs facilitated by COST Action CM1103 (2011-2015).The actions of many drugs involve enzyme inhibition.
Ramsay, Rona R., Tipton, Keith F.
core   +1 more source

Protective effects of gallic acid against chronic cerebral hypoperfusion-induced cognitive deficit and brain oxidative damage in rats [PDF]

open access: yes, 2014
Free radical induced neural damage is implicated in cerebral hypoperfusion disorders and antioxidants have protective effects. In the present study, we examined the effect of gallic acid (GA; 100 mg/kg, p.o. for 10 days) on cognitive deficit and cerebral
Farbood, Yaghoub.   +4 more
core   +1 more source

Development of 2-Methoxyhuprine as Novel Lead for Alzheimer’s Disease Therapy

open access: yesMolecules, 2017
Tacrine (THA), the first clinically effective acetylcholinesterase (AChE) inhibitor and the first approved drug for the treatment of Alzheimer’s disease (AD), was withdrawn from the market due to its side effects, particularly its hepatotoxicity ...
Eva Mezeiova   +16 more
doaj   +1 more source

Bioactive Metabolites from Propolis Inhibit Superoxide Anion Radical, Acetylcholinesterase and Phosphodiesterase (PDE4) [PDF]

open access: yes, 2013
Cycloartane-triterpenes (cycloartenol, 3α-cycloartenol-26-oic acid and 3β-cycloartenol-26-oic acid) together with α-amyrin acetate and flavonoids (pinostrobin, tectochrysin and chrysin) were isolated from Egyptian propolis for the first time.
Abd El-Hady, Faten K.   +5 more
core  

Formulation of gliclazide using self-nano-emulsification technology [PDF]

open access: yes, 2018
Self-nano-emulsifying drugs delivery systems present an effective drug delivery system for the formulation of a hydrophobic drug with poor water-solubility.
Abdel-Aziz, Farah   +4 more
core  

Obtenção e caracterização de micropartículas de PHB/Qt/Cetoprofeno [PDF]

open access: yes, 2010
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Química.O objetivo do presente trabalho foi obter micropartículas compostas com um fármaco e controlar liberação do mesmo, otimizando a ...
Lins, Luanda Chaves Vieira
core  

Isolation of endophytic fungi and screening of Huperzine A–producing fungus from Huperzia serrata in Vietnam

open access: yesScientific Reports, 2019
Huperzine A (HupA), a natural Lycopodium alkaloid derived from Huperzia serrata (Thunb. ex Murray) Trev. plants, is a highly active acetylcholinesterase inhibitor and a key compound used for treating Alzheimer’s disease (AD).
Thanh Thi Minh Le   +5 more
semanticscholar   +1 more source

1,3-Dicarbonyl compounds in stereoselective domino and multicomponent reactions

open access: yes, 2010
International audienceModern organic synthesis focuses on the discovery and the development of stereoselective multiple bond-forming transformations allowing the creation of several covalent bonds in a single operation.
Bonne, Damien   +3 more
core   +4 more sources

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