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The scoop on brain health dietary supplement products containing huperzine A
, 2020 Context: Public health concerns are emerging surrounding huperzine A commonly found in dietary supplements. We sought to determine the actual content of products claiming to contain huperzine A and whether the ingredients on the supplement facts labels ...
Cindy Crawford (528683) +5 more
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Frontiers in Plant ScienceIntroductionCrop rotation of tobacco with other crops could effectively break the negative impact of continuous tobacco cropping, but the mechanisms of intercropping system effects on tobacco, especially on the rhizosphere, are not clear.MethodsIn this ...
Ming Liu +9 more
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Structural analogs of huperzine A improve survival in guinea pigs exposed to soman
, 2013 Chemical warfare nerve agents such as soman exert their toxic effects through an irreversible inhibition of acetylcholinesterase (AChE) and subsequently glutamatergic function, leading to uncontrolled seizures.
Doctor, B. +12 more
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Huperzine A decreased mitochondrial accumulation of Aβ42.
, 2015 A. The schematic diagram of the proportion of mitochondria-enriched fraction Aβ42 in total intracellular Aβ42. B. Effect of huperzine A on the level of Aβ42 in different subcellular fractions (N = 4).
Hai Yan Zhang (589189) +7 more
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European Cells & MaterialsBackground: Huperzine A (HupA), a potent and selective acetylcholinesterase inhibitor with neuroprotective properties, faces significant clinical challenges in Alzheimer’s disease (AD) management.
Jianfei Wu +8 more
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Neuropsychiatric Disease and Treatment, 2015 Haiying Lu,1,* Mei Jiang,2,* Lei Lu,3 Guo Zheng,1 Qiang Dong3 1Department of Neurology, Nanjing Children’s Hospital, Nanjing Medical University, Nanjing, 2Department of Neurology, Shanghai Pudong New Area Gongli Hospital, Shanghai, 3Department of ...
Lu H, Jiang M, Lu L, Zheng G, Dong Q
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A concise and convergent (formal) total synthesis of huperzine A
, 2007 The first convergent synthesis of the tricyclic skeleton of huperzine A is described and includes, as the key step, an efficient regioselective intramolecular Heck reaction of 2-(tert-butyldimethylsillyoxymethyl)-6-(2-methoxy-5-bromopyridin-6-yl ...
Kelly, S., Lucey, C., Mann, John
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Huperzine A ameliorates the spatial working memory impairments induced by AF64A
, 1995 Huperzine A, a novel, potent, reversible, and selective acetylcholinesterase (AChE) inhibitor has been expected to be superior to other AChE inhibitors now for the treatment of memory deficits in patients with Alzheimer’s disease.
Han, Yi Fan, Xiong, Zhi Qi, Tang, Xi Can
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Australasian Huperzia as potential sources of Huperzine alkaloids
, 2010 © 2010 Wei-Han LimThe Lycopodiaceae is an ancient and cosmopolitan family of fern allies that include an estimated 35 Huperzia species occurring throughout the South-East Asian and Australian region.
Lim, Wei-Han
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Clinical Interventions in Aging, 2018 Jinghong Liang, Jiayu Li, Ruixia Jia, Yingquan Wang, Rongkun Wu, Hongbo Zhang, Lei Hang, Yong Xu Department of Child Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow ...
Liang JH +7 more
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