Eco-friendly RP-HPLC method for determination of diazepam in coated tablet
Macedonian Journal of Chemistry and Chemical Engineering, 2023 A new eco-friendly RP-HPLC method for determining diazepam in coated tablets was developed and validated. The separation was achieved on a Lichrosper® 100 RP-18 (250 mm × 4 mm, 5 µm particle size) using the isocratic elution mode with a mobile phase ...
Marija Tomić +6 more
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Macedonian Journal of Chemistry and Chemical Engineering, 2021 Fast and simple closed-vessel microwave-assisted digestion procedure was developed for decomposition of three pharmaceutical dosage forms of ibuprofen such as tablets, suspension and gel, prior to elemental impurity analysis by one robust and precise ...
Katerina Jancevska +4 more
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Providing clinical evidence under the MDR 2017/745: New challenges for manufacturers in medical device industry [PDF]
Arhiv za farmaciju, 2019 Providing necessary clinical evidence throughout the systems for Clinical Evaluation and Post-Market Surveillance in accordance with new MDR 2017/745 requirements imposes new challenges for manufacturers in medical device industry.
Ivanovska Elena +5 more
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Macedonian Journal of Chemistry and Chemical Engineering, 2022 This research highlights the specificity of the new stability-indicating method developed to evaluate the impurity profile of Atorvastatin film-coated tablets. The proposed method has the ability to capture any possible changes that may occur during the
Elena Trajchova Kovachovska +6 more
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Investigation of the influence of critical process parameters in roller compaction process on physical properties of granules and tablets using design of experiments [PDF]
Arhiv za farmaciju, 2020 Different granulation methods are used in the pharmaceutical industry, mainly divided as wet or dry granulation. Although roller compaction is a widely used dry granulation process, the evaluation of critical process parameters has proven challenging ...
Atanaskova Elizabeta +2 more
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A study of The effect of the aqueous extract of different organs of Peganum harmala L. on the germination and growth of Amaranthus retroflexus L. and Chenopodium album L. [PDF]
علوم و فناوری بذر ایران, 2023 This research was conducted in order to investigate the effect of aqueous extract of different organs of harmel (Peganum harmala) on the growth and germination of Amaranthus retroflexus and Chenopodium album in two experiments (laboratory and greenhouse)
Reza Rezvani, Alireza Dadkhah
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Complaints management in the pharmaceutical industry: A Case Study [PDF]
Makedonsko Farmacevtski BiltenEffective complaints management in the pharmaceutical industry is one of the cornerstones for ensuring product quality, regulatory compliance, and customer safety and satisfaction.
Marija Stojanovska +4 more
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How cinchona alkaloid-derived primary amines control asymmetric electrophilic fluorination of cyclic ketones. [PDF]
, 2014 The origin of selectivity in the α-fluorination of cyclic ketones catalyzed by cinchona alkaloid-derived primary amines is determined with density functional calculations.
Houk, KN, Lam, Yu-hong
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Workflow for investigation of Out of Specification results in physico-chemical laboratory in Alkaloid [PDF]
Makedonsko Farmacevtski BiltenThe efficient and accurate investigation of Out of Specification (OOS) results is crucial in maintaining the reliability and quality of products in a physico-chemical laboratory.
Andrea Alagjozovska +8 more
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Phytochemical characterization of Tabernanthe iboga root bark and its effects on dysfunctional metabolism and cognitive performance in high-fat-fed C57BL/6J mice [PDF]
, 2018 Preparations of the root bark of Tabernanthe iboga have long been used in Central and West African traditional medicine to combat fatigue, as a neuro-stimulant in rituals, and for treatment of diabetes. The principal alkaloid of T.
Akinyeke, Tunde +11 more
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