Results 11 to 20 of about 168,537 (253)

Identification of 5‑HT2 Serotonin Receptor Modulators through the Synthesis of a Diverse, Tropane- and Quinuclidine-alkaloid-Inspired Compound Library

, 2023
The recombination of natural product (NP) fragments in unprecedented ways has emerged as an important strategy for bioactive compound discovery. In this context, we propose that privileged primary fragments predicted to be enriched in activity against a ...
Anders A. Jensen (709631), Ruwei Yao (1392235), Libin Zhou (692565), Nicklas P. Hovendal (16819002), Mariusz Kubus (4813806), Luca Laraia (1811935), Hogan P. Bryce-Rogers (16818999), Katrine Schultz-Knudsen (15387791), Trond Ulven (176789), Henrik Pedersen (109842)   +9 more
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Eco-friendly RP-HPLC method for determination of diazepam in coated tablet

Macedonian Journal of Chemistry and Chemical Engineering, 2023
A new eco-friendly RP-HPLC method for determining diazepam in coated tablets was developed and validated. The separation was achieved on a Lichrosper® 100 RP-18 (250 mm × 4 mm, 5 µm particle size) using the isocratic elution mode with a mobile phase ...
Marija Tomić, Marijana Božinovska, Nataša Anevska-Stojanovska, Jelena Lazova, Rumenka Petkovska, Liljana Anastasova, Natalija Nakov   +6 more
doaj   +1 more source

Structure-activity relationships of synthetic analogs of jasmonic acid and coronatine on induction of benzo[c]phenanthridine alkaloid accumulation in Eschscholzia californica cell cultures [PDF]

, 2000
A facile test system based on the accumulation of benzo[c]phenanthridine alkaloids in Eschscholzia californica cell suspension culture (an indicator of defense gene activation) has been used to analyze a series of synthetic compounds for elicitor-like ...
Blechert, S., Kutchan, T. M., Schrader, T. von, Haider, G., Füßlein, M.   +4 more
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Cinchona-Alkaloid-Derived NN Ligands and Achiral Phosphines for Iridium-Catalyzed Asymmetric Hydrogenation of Heteroaromatic and α‑Chloroheteroaryl Ketones

, 2023
A concise synthesis of cinchona-alkaloid-derived NN ligands bearing alkyl substituents on chiral nitrogen atoms was described. Iridium catalysts containing new chiral NN ligands and achiral phosphines were effective for the asymmetric hydrogenation of ...
Qian Xu (119888), Linlin Li, Chun Li, Lin Zhang, Linlin Li (180556), Xin Meng, Hao Sun, Pinli Dai, Jie Tian (20496), Xin Meng (140656), Jie Tian, Qian Xu, Qian Chen (18883), Hao Sun (14095), Pinli Dai (15905764), Lin Zhang (8926), Qian Chen, Chun Li (57810)   +17 more
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Alkaloid-Catalyzed Enantioselective [3 + 2] Cycloaddition of Ketenes and Azomethine Imines

, 2016
A new asymmetric synthesis of bicyclic pyrazolidinones through an alkaloid-catalyzed formal [3 + 2] cycloaddition of in situ generated ketenes and azomethine imines is described.
Nessan J. Kerrigan (1575376), Kraig A. Wheeler (1590007), Mukulesh Mondal (1575367)   +2 more
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Isolation and X-ray crystal structure of tetrahydroisoquinoline alkaloids from Calycotome villosa Subsp. intermedias [PDF]

, 2004
Two tetrahydroisoquinoline alkaloids were extracted from the alkaloid fraction of a methanol extract of the seeds of Calycotome Villosa Subsp. intermedia.
Bolte, Michael, El Alami, Rachid, El Bali, Brahim, Messouri, Ibtissam, Bouktaib, Mohamed, Rachid El Alami, Brahim El Bali, Michael Bolte, El Antri, Ali, Mohamed Bouktaib, Ibtissam Messouri, Lachkar, Mohammed, Mohammed Lachkar, Ali El Antri   +13 more
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The Relationship between Structurally Different Pyrrolizidine Alkaloids and Western Flower Thrips Resistance in F2 Hybrids of Jacobaea vulgaros and Jacobaea aquatica [PDF]

, 2011
Segregating plant hybrids often have more ecological and molecular variability compared to parental species, and are therefore useful for studying relationships between different traits, and the adaptive significance of trait variation.
Vrieling, K., Kirk, H., Cheng, D., Kirk, H.E., Klinkhamer, P.G.L., Mulder, P.P.J.   +5 more
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The Ir-Catalyzed Asymmetric Hydrogenation of α‑Halogenated Ketones Utilizing Cinchona-Alkaloid-Derived NNP Ligand to Produce (R)- and (S)‑Halohydrins

, 2022
The asymmetric hydrogenation of α-halogenated ketones with iridium catalyst was developed, utilizing easily accessed cinchona-alkaloid-based NNP ligands.
Jie Tian (20496), Qian Xu (119888), Nana Ma (466985), Linlin Li (180556), Qian Chen (18883), Hao Sun (14095), Lin Zhang (8926), Li Li (14993), Chun Li (57810)   +8 more
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Optimization of sample preparation and analytical performance evaluation for a model polar compound in hydroxypropyl methycelulose-based controlled-release tablets [PDF]

Arhiv za farmaciju
Controlled-release (CR) tablets based on hydroxypropyl methylcellulose (HPMC) provide numerous therapeutic advantages, but pose significant analytical challenges during the assay of polar active substances due to the polymer's high swelling capacity and ...
Bozhinovska Marijana, Achkoska Tina, Atanasova Ana, Antovska Packa, Gigopulu Olga, Poceva-Panovska Ana   +5 more
doaj   +1 more source

Effect of hydrogen bonding and complexation with metal ions on the fluorescence of luotonin A [PDF]

, 2013
Fluorescence characteristics of a biologically active natural alkaloid, luotonin A (LuA), were studied by steady-state and time-resolved spectroscopic methods.
Biczók, László, Miskolczy, Zsombor
core   +1 more source