Results 41 to 50 of about 168,537 (253)
Advanced Science, EarlyView.Integration of the D‐genome reshapes gene transcription, chromatin architecture, and the metabolome of hexaploid wheat, leading to enhanced adaptability to salt, UV‐B, and alkali stress. ABSTRACT The hybridization‐led integration of the D‐genome into domesticated tetraploid wheat gave rise to allohexaploid wheat, the most cultivated wheat globally ...
Yanyan Liu +23 more
wiley +1 more source
Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of Ketones
Most ligands applied for asymmetric hydrogenation are synthesized via multistep reactions with expensive chemical reagents. Herein, a series of novel and easily accessed cinchona-alkaloid-based NNP ligands have been developed in two steps.
Chong Zhao (495389) +8 more
core +1 more source
Advanced Science, EarlyView.Nuciferine directly binds the C2 domain of cPLA2, impairing its Ca2+‐dependent membrane translocation and activation. By suppressing arachidonic acid release and downstream pro‐inflammatory eicosanoid production, nuciferine attenuates NF‐κB signaling and inflammatory hepatocarcinogenesis, revealing cPLA2 as a direct molecular target underlying its ...
Jing Sun +12 more
wiley +1 more source
Advanced Intelligent Discovery, EarlyView.Artificial intelligence is redefining network pharmacology (NP). By integrating knowledge graph engineering, geometric deep learning, multiomics anchoring, and generative reasoning, AI‐driven NP (AI‐NP) transforms static target mapping into dynamic, predictive modeling.
Cong Wang +9 more
wiley +1 more source
American Journal of Botany, EarlyView.Abstract Premise The soil depth of underground storage organs (USOs) of geophytes involves cost–benefit trade‐offs and may relate to USO age, size, and disturbances such as fire and herbivory. Yet determinants of USO depth are poorly studied. We posit that belowground mammalian predation of USOs is a selective force for the positive relationship ...
Tineke Kraaij +4 more
wiley +1 more source
Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of β‑Keto Ester
The Ir-catalyzed asymmetric hydrogenation of β-keto esters with Cinchona-alkaloid-derived NNP ligands has been developed. β-Hydroxy esters of opposite configuration were afforded smoothly with 91.5–99.1 and 81.6–99.3% ee, respectively, using NNP L2 and ...
Jie Tian (20496) +8 more
core +1 more source
A novel alkaloid from Gaultheria nummularioides
, 2007 A novel alkaloid, gaultherialine A (1), along with twenty-seven known compounds were isolated from the whole plants of Gaultheria nummularioides D. Don. The structure of the new alkaloid was elucidated as 7,8-diMethoxy-1-(4-methoxyphenyl)-4,5-dihydro-2H ...
Yang, MF +4 more
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Dasycarine, a new quinoline alkaloid from Dictamnus dasycarpus [PDF]
, 2000 Dasycarine, a new quinoline alkaloid along with five known compounds, dictamine, dihydroobacunone, obacunone, fraxinellone and beta-sitosterol, were isolated from Dictamnus dasycarpus. The structure of dasycarine was identified as 4, 5, 8- trimethoxyl -3-
Chen, J +4 more
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Alcalóides ciclopeptídicos: diversas abordagens no estudo da estereoquímica baseados na franganina [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, 2011O alcalóide ciclopeptídico franganina foi isolado da Discaria americana pertencente à família Rhamnaceae ...
Oliveira, Leonardo Henrique de
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Aspeverin, a New Alkaloid from an Algicolous Strain of Aspergillus versicolor [PDF]
, 2013 A novel carbamate- and cyano-containing alkaloid, aspeverin (1), was isolated from the culture of an algicolous Aspergillus versicolor strain (dl-29).
Nai-Yun Ji +7 more
core +1 more source