Journal of Analytical Methods in Chemistry, 2019 The purpose of this study was to develop and validate a discriminative dissolution method for the metformin film-coated tablet with immediate release of the active substance that belongs to class III of the Biopharmaceutical Classification System (BCS ...
Ivana Mitrevska +5 more
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Analytical Quality by Design approach in development and optimization of HPLC method for assay of angiotensin – converting enzyme inhibitor in tablets [PDF]
Makedonsko Farmacevtski BiltenImplementation of analytical quality by design approach is a helpful tool in development of a robust analytical method which is applicable throughout the lifecycle of the product.
Veronika Popovska Jakimovska +7 more
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Cyclopropanation of carbon-carbon double bonds in ring d of ergot alkaloids [PDF]
, 2013 Some ergot alkaloid derivatives containing a double bond in ring D have been reacted with diazomethane/palladium diacetate reagent to result in formation of a fused cyclopropane ring.
Dörnyei, Gábor +5 more
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, 2017 Cephalotaxus alkaloids represent a family of plant secondary metabolites known for 60 years. Significant activity against leukemia in mice was demonstrated for extracts of Cephalotaxus. Cephalotaxine (CET) (1), the major alkaloid of this series was isolated from Cephalotaxus drupacea species by Paudler in 1963.
Pérard-Viret, Joelle +4 more
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Fungal alkaloid occurrence during seedling establishment and early growth in Lolium perenne seedlings infected with Epichloë festucae var. lolii and the influence of adult Argentine stem weevil (Listronotus bonariensis) feeding on alkaloid concentrations : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science (MSc) in Agriculture Science at Massey University, Palmerston North, New Zealand [PDF]
, 2016 Fungal endophytes of the genus Epichloë often form stable, symbiotic, and mutualistic relationships with grasses of the Pooideae, including perennial ryegrass (Lolium perenne L.).
Ruppert, Katrin Gabriela
core
GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway [PDF]
, 2016 Steroidal glycoalkaloids (SGAs) are cholesterol-derived molecules produced by solanaceous species. They contribute to pathogen defence but are toxic to humans and considered as anti-nutritional compounds.
Aharoni, Asaph +13 more
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Nat. Prod. Rep., 2014 This review focuses on the isolation and synthesis of natural products containing a 1-azabicyclo[3.3.0]octane core (July 2001 to December 2012).
Robertson, J, Stevens, K
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Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Optimized genotyping method for identification of bacterial contaminants in pharmaceutical industry
Acta Pharmaceutica, 2016 Microbiological control is of crucial importance in the pharmaceutical industry regarding the possible bacterial contamination of the environment, water, raw materials and finished products. Molecular identification of bacterial contaminants based on DNA
Stamatoski Borche +4 more
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Total Synthesis and Structural Revision of the Alkaloid Incargranine B [PDF]
, 2013 Seeing double: Consideration of the biosynthetic origins of incargranineB, which was originally assigned an unprecedented indolo[1.7]naphthyridine structure, led to the proposal of a dipyrroloquinoline framework as a more biosynthetically feasible ...
Bates +8 more
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