Results 71 to 80 of about 2,786 (199)

Infraspecific Variation of Huperzine A and B in Icelandic Huperzia selago Complex [PDF]

, 2018
Publisher's version (útgefin grein)The alkaloids huperzine A and huperzine B were originally isolated from the Chinese club moss Huperzia serrata.
Olafsdottir, Elin Soffia, Sun, Hang, Deng, Tao, Omarsdottir, Sesselja, Heiðmarsson, Starri, Xu, Maonian, Wasowicz, Pawel, Thorsteinsdóttir, Margrét   +7 more
core   +2 more sources

Exposure the Hazardous Potential of Quinalphos: An In‐Depth Analysis for Environmental and Biological Effects on Human Health

IET Systems Biology, Volume 20, Issue 1, January/December 2026.
This study elucidates pesticide docking onto proteins encoded by differentially expressed genes, revealing interaction networks involving chemicals, genes, proteins, drugs and diseases. It highlights structural insights, regulatory pathways and potential therapeutic or environmental implications, providing a comprehensive understanding of the ...
Jyoti Kant Choudhari, Biju Prava Sahariah, Anand Kumar Jayapal, Jyotsna Choubey, Abhishek Tripathi   +4 more
wiley   +1 more source

Reference gene selection for real‐time quantitative PCR assays in different tissues of Huperzia serrata based on full‐length transcriptome sequencing

Plant Direct, 2021
Huperzia serrata (H. serrata) produces various types of effective lycopodium alkaloids, especially Huperzine A (HupA), which is a promising drug for the treatment of Alzheimer's disease.
Yanping Fu, Fei Niu, Hui Jia, Yanli Wang, Bin Guo, Yahui Wei   +5 more
doaj   +1 more source

Evaluation of acetylcholinesterase and butyrylcholinesterase inhibitory activity of Huperzine-A; in silico and in vitro studies [PDF]

, 2019
The present study is focused on exploring the Acetylcholinesterase and Butyrylcholinesterase inhibitory activity of Huperzine-A in silico and in vitro. In this study, Huperzine-A-A was docked with Acetylcholinesterase and Butyrylcholinesterase.
Kohli, Seema, Sharma, RK, Upadhyay, Shagun Dubey, Ahmad, Yusra   +3 more
core   +1 more source

Hesperidin, Hesperetin, and Naringenin in Retinal Pathophysiology: Molecular Crosstalk Between Metabolic Dysfunction, Neuroinflammation, and Therapeutic Signaling in Diabetic Retinopathy

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Diabetic retinopathy (DR) is a leading cause of blindness worldwide, characterized by retinal vascular dysfunction, oxidative stress, inflammation, and neuronal degeneration. Flavonoids such as hesperidin (HSD), hesperetin (HST), and naringenin, commonly found in citrus fruits, have shown promise in mitigating DR through multiple molecular mechanisms ...
Guangling Feng, Zhicheng Huang, Farzam Kiarasi   +2 more
wiley   +1 more source

The chemical structure of Huperzine A.

, 2013
The chemical structure of Huperzine A.
Zhang-Qian Wang (403474), Shao-Hua Shu (403475), Wen-Juan Wang (403476), Xin-Mei Zhao (403473), Mo Wang (152951), Young-Joon Ahn (403478), Hai-Jie Xu (403477), Xuebo Hu (334720)   +7 more
core   +1 more source

From Demyelination to Intervention: Natural Compounds as Emerging Therapeutic Targets in Multiple Sclerosis Neuroinflammation

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Multiple sclerosis (MS) is a chronic immune‐mediated inflammatory demyelinating disease of the central nervous system (CNS), characterized by multifocal lesions, axonal damage, and progressive neurological dysfunction, imposing a heavy burden on patients and healthcare systems.
Zhiyong Long, Qianyue Yang, Yonghe Wu, Lifei Wan, Liuting Zeng, Lingyun Sun, Poorani Gurumallesh   +6 more
wiley   +1 more source

New Syntheses of rac-Huperzine A and its rac-7-Ethyl-Derivative. Evaluation of Several Huperzine A Analogues as Acetylcholinesterase Inhibitors

, 2000
rac-Huperzine A, its rac-7-ethyl-derivative and two regioisomeric analogues have been prepared through synthetic sequences involving the elaboration of the pyridone ring in a late stage, by reaction of an intermediate pyrrolidine enamine with ...
Badia, Albert, Contreras, Joan, Solans, Xavier, Vivas, Nuria María, Morral-Cardoner, Jordi, Font-Bardia, Mercè, Camps, Pelayo, Muñoz-Torrero, Diego, El Achab, Rachid   +8 more
core   +1 more source

Huperzine A attenuates apoptosis and mitochondria-dependent caspase-3 in rat cortical neurons [PDF]

, 2002
The neuroprotection of huperzine A against apoptosis was investigated. In cultures of rat primary cortical neurons, neuronal apoptosis was induced by serum deprivation for 24 h, which was accompanied by enhanced caspase-3 activity and the release of ...
Xi Can Tang, Jin Zhou, Zhou, Jin, Tang, Xi Can   +3 more
core   +1 more source

Huperzine A: a natural acetylcholinesterase inhibitor with multifunctional neuroprotective effects

Beni-Suef University Journal of Basic and Applied Sciences
Background Huperzine A, a naturally derived compound, has garnered interest for its capacity to inhibit cholinesterase with multifaceted neuroprotective effects and is obtained from Huperzia serrata (Chinese club moss plant).
Suvaiv, Kuldeep Singh, Syed Misbahul Hasan, Arun Kumar, Abdullah khan, Mo. Shahanawaz, Syed Mehdi Hasan Zaidi, Kausal Verma   +7 more
doaj   +1 more source