Results 61 to 70 of about 2,786 (199)
Chemical structure of huperzine A.
, 2015 Chemical structure of huperzine A.
Wenjuan Wang (31234) +10 more
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Recent Advances in Carbonyl–Olefin and Carbonyl–Alkyne Metathesis Reactions
ChemistryEurope, Volume 4, Issue 4, April 2026.Carbonyl–olefin and carbonyl–alkyne metathesis enable atom‐economic C–C bond formation beyond classical olefin metathesis. This review highlights recent advances in photochemical, Lewis‐acid, Brønsted‐acid, and organocatalytic strategies, mechanistic insights, and synthetic applications, showcasing carbonyl metathesis as a versatile platform for modern
Komal Kalonia +2 more
wiley +1 more source
Protective effect of huperzine A on phenytoin induced cognition impairment: Behavioral and biochemical study [PDF]
, 2022 205-213Phenytoin, a drug of choice for Epilepsy is also known for its adverse effects. The most common adverse effect due to phenytoin is cognition impairment.
Dubey (Upadhyay), Shagun
core
Total Synthesis of (−)-Huperzine A
, 2016 The total synthesis of (−)-huperzine A was accomplished in 23 steps from a commercially available anhydride. Our synthetic route features a facile construction of the bicyclo[3.3.1] skeleton equipped with proper functionalities to introduce the remaining
Takahiro Koshiba (1843504) +2 more
core +2 more sources
Physiological Reports, 2022 Acetylcholine (ACh) may be involved in the regulation of ovarian functions. A previous systemic study in rats showed that a 4‐week, intrabursal local delivery of the ACh‐esterase blocker Huperzine‐A increased intraovarian ACh levels and changed ovarian ...
Fernanda C. Cuevas +8 more
doaj +1 more source
Alzheimer's disease drug development pipeline: 2026
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 2, April/June 2026.Abstract INTRODUCTION Discovery and development of new therapies for Alzheimer's disease (AD) are urgently needed to address the world's growing population of individuals on the AD pathophysiological continuum. Clinicaltrials.gov is a resource for studying drugs in development for treatment of AD. RESULTS There are currently 158 drugs in 192 AD trials.
Jeffrey L. Cummings +6 more
wiley +1 more source
Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.This PROSPERO‐registered review analysed 37 RCTs on neuronutraceuticals for Alzheimer's disease. Despite diverse targets—amyloid/tau, inflammation, oxidative stress, metabolism, synaptic plasticity, cholinergic and hormonal—the evidence was of low quality. RoB2 flagged attrition (86.5%) and reporting bias (81%). Current data do not support clinical use;
Mehmet Akif Topcuoglu, Esen Saka
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Correction to Total Synthesis of (−)-Huperzine A
, 2016 Correction to Total Synthesis of ...
Takahiro Koshiba (1843504) +2 more
core +1 more source
Electronic Journal of Biotechnology, 2015 Background: An endophytic fungus lives within a healthy plant during certain stages of, or throughout, its life cycle. Endophytic fungi do not always cause plant disease, and they include fungi that yield different effects, including mutual benefit, and ...
Zhejian Wang +6 more
doaj +1 more source
Rapid Structural Analysis of Natural Products Using MicroED
Small, Volume 22, Issue 15, 12 March 2026.The cryoEM method, MicroED used for rapid analysis and structure determination of natural products that remained unattainable by other structural biology methods ABSTRACT Structural analysis of natural products remains challenging due to their inherent complexity and limited availability.
Jieye Lin +3 more
wiley +1 more source