Activation of spinal cord microglia contributes to the development of peripheral nerve injury-induced neuropathic pain. However, the molecular mechanisms underlying microglial function in neuropathic pain are not fully understood.
Jiyun Peng +10 more
semanticscholar +1 more source
Teaching For and About Critical Pedagogy in the Post-Secondary Classroom
While there is a body of literature that considers the theory of critical pedagogy, there is significantly less literature that specifically addresses the ways in which professors attempt to apply this theory in practice.
Mary Breunig
doaj
Functions and Mechanisms of the Voltage-Gated Proton Channel Hv1 in Brain and Spinal Cord Injury
The voltage-gated proton channel Hv1 is a newly discovered ion channel that is highly conserved among species. It is known that Hv1 is not only expressed in peripheral immune cells but also one of the major ion channels expressed in tissue-resident ...
Junyun He, Rodney M. Ritzel, Junfang Wu
semanticscholar +1 more source
The Public and the Profession’s Perception of Social Work
The social work profession has long been concerned about its mission and perception. The two interests go hand in hand, because to have an effect on how we as social workers are viewed, we must be self-aware about who we are and what we do.
Jeffrey Olin
doaj
Attività del giudice di pace in ambito penale: una ricerca presso il Tribunale di Bologna / The activity of the Judge of the Peace under the criminal jurisdiction: a study carried out in the Law Court of Bologna / L'activité du juge de paix en matière pénale: une étude empirique auprès du Tribunal de Bologne [PDF]
This article analyses the reform of the Justice of the Peace, provided for by the legislative decree n. 274/2000. This law introduces some changes in the Italian justice system: a faster proceeding than in other Courts, the institutions of the immediate ...
Bianchini Elena
doaj
HIFs: New arginine mimic inhibitors of the Hv1 channel with improved VSD–ligand interactions
Zhao et al. leverage the analysis of local conformational changes in a mutant Hv1 channel to inform the design of new inhibitors. These arginine mimics have improved interaction with the voltage-sensing domain and inhibit the wild-type channel with ...
Chang Zhao +8 more
semanticscholar +1 more source
Strengths-Based Social Work: Proposing Protective and Engagement Practice with Older Adults [PDF]
This article proposes Strengths-Based Protective (SB-P) and Strengths-Based Engagement (SB-E) social work practice model with older adults with particular reference to living in older care homes.
Vishal M. V.
doaj
The voltage sensor is responsible for ΔpH dependence in Hv1 channels
Significance Acid extrusion in various types of cells and the reactive oxygen species production by the NADPH oxidase in phagocytes and microglia are mediated by the voltage-gated proton channel (Hv1).
Emerson M. Carmona +8 more
semanticscholar +1 more source
Acne vulgaris is a prevalent chronic inflammatory skin disease, most common in adolescence and often persisting into adulthood, leading to severe physical and psychological impacts. The primary etiological factor is Cutibacterium acnes infection.
Xu Li +6 more
semanticscholar +1 more source

