Results 31 to 40 of about 5,264 (268)

Synchronizing the Osteochondral Regeneration Process through Spatial Patterning of Stable and Hypertrophic Cartilage Organoids

open access: yesAdvanced Materials, EarlyView.
Zonated osteochondral assembloid implants are engineered through scaffold‐free spatial assembly of induced pluripotent stem cell (iPSC)‐derived chondrocyte organoids and periosteum‐derived osteogenic organoids. Implanted into full‐thickness rat osteochondral defects, they promote hyaline‐like cartilage repair, support subchondral bone formation with ...
Liuqi Peng   +3 more
wiley   +1 more source

THROMBOTIC THROMBOCYTOPENIC PURPURA

open access: yesEurasian Journal of Medicine, 2019
Thrombotic thrombocytopenic purpura is characterized by microangiopathic hemolytic anemia, thrombocytopenia, fever, neurologic abnormalities and renal dysfunction.The typical pathologic lesion, widespread hyalin oclusions in arterioller.
Ali Rıza Odabaş   +2 more
doaj  

Mosaicplasty procedure and fascia lata grafting method for the treatment of isolated osteochondral lesions Experimental study in sheep

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Articular cartilage has a limited capacity for repair.We investigated the effect of mosaieplasty and fascia lata grafting method on the healing of full-thickness osteochondral defects in adult Turkish(Karaman) sheep.Double defects,ten milimeters wide by ...
Bulent Aksoy   +7 more
doaj  

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

Karyotyping and localization of genes on the chromosomes of the sea urchins, Strongylocentrotus drobachiensis and Strongylocentrotus purpuratus [PDF]

open access: yes, 2009
The purple sea urchin, Strongylocentrotus purpuratus , is an important model for probing gene interactions during animal development and is the only non-chordate deuterostome for which a complete genome sequence is available.
Eno, Celeste Chloe
core   +2 more sources

Maladies des arbres à quinquina en Guinée française [PDF]

open access: yes, 1956
Chevaugeon Jean, Merny Georges. Maladies des Arbres à Quinquina en Guinée Française. In: Journal d'agriculture tropicale et de botanique appliquée, vol. 3, n°11, novembre 1956. pp.
Chevaugeon, Jean, Merny, Georges
core   +1 more source

Sorne observations on the enzootic pneurnonias of larnbs and kids [PDF]

open access: yesEurasian Journal of Veterinary Sciences
In vicinity of Elazığ, 17 lambs and 3 kids with pneumonia were examined. Macroscopically, the foci of pneumonia in lugs were voluminous or collapsed according to the nature and duration of the disease.
Harun ÖZER, H. Basri G ÜLCÜ
doaj  

The role of pro- inflammatory cytokines and the enzyme element of antioxidant system in the destruction of hyalin cartilage at the early stages of primary gonarthrosis [PDF]

open access: yesСаратовский научно-медицинский журнал, 2018
Aim: comparative assessment of the state of joint (hyaline) cartilage, pro-inflammatory component of cytokine profile and enzyme element of blood antioxidant system in healthy individuals and patients at the early stages of gonarthrosis.
Karyakina Е.М.   +4 more
doaj  

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

open access: yesAdvanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang   +23 more
wiley   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan   +10 more
wiley   +1 more source

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