Results 41 to 50 of about 2,398 (262)
Advanced Science, EarlyView.This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li +15 more
wiley +1 more source
Advanced Science, EarlyView.In this study, MPDA NPs were engineered to encapsulate CTT. To further increase renal accumulation of CTT, L‐serine was conjugated to the surface of the MPDA nanoparticles (CTT/MPDA@L‐Ser NPs). CTT/MPDA@L‐Ser NPs inhibit DPEP1 activity, thereby restoring ferroptosis defense mechanisms through upregulation of GPX4 and SLC7A11 expression, ultimately ...
Wanbing Qin +12 more
wiley +1 more source
Terapi Surfaktan pada Penyakit Membran Hyalin
Jurnal Kedokteran dan Kesehatan, 2018 Penyakit membran hialin (PMH) atau Respiratory Distress Syndrome (RDS) adalah suatu sindroma yang terjadi pada bayi prematur karena imaturitas struktur paru dan insufisiensi produksi surfaktan.
Sri Utami Fajariyah +2 more
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The Effect of Arabic Gum on Gentamicin Nephrotoxicity in Mice: A Pathological Study
Medicinski GlasnikAim To investigate the effect of Arabic gum on gentamycin nephrotoxicity in mice kidney.Methods Forty (40) mice were divided into five groups, eight mice in each. Group one (G1) stands for the negative control group. The second one (G2) was injected with
Liqaa Alhyali +2 more
doaj +1 more source
Advanced Science, EarlyView.The PS‐QRC nanoprobe employs L‐serine as a targeting ligand for kidney injury molecule‐1 (KIM‐1) to achieve accumulation in injured renal tissues. Upon activation by reactive oxygen species (ROS), it undergoes a self‐amplifying cascade to release fluorophores for near‐infrared fluorescence (NIRF) imaging, enabling ultra‐early diagnosis of acute kidney ...
Yahui Chen +10 more
wiley +1 more source
THROMBOTIC THROMBOCYTOPENIC PURPURA
Eurasian Journal of Medicine, 2019 Thrombotic thrombocytopenic purpura is characterized by microangiopathic hemolytic anemia, thrombocytopenia, fever, neurologic abnormalities and renal dysfunction.The typical pathologic lesion, widespread hyalin oclusions in arterioller.
Ali Rıza Odabaş +2 more
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The use of chondral rib in the treatment of articular cartilage defects
Acta Orthopaedica et Traumatologica Turcica, 2021 Objectives: Many different methods have been proposed for the repair of articular cartilage defects. Among these, cartilage transplantation is one of the most promising methods.
Hasan Bombaci +3 more
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Advanced Science, EarlyView.An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang +8 more
wiley +1 more source
Sorne observations on the enzootic pneurnonias of larnbs and kids [PDF]
Eurasian Journal of Veterinary SciencesIn vicinity of Elazığ, 17 lambs and 3 kids with pneumonia were examined. Macroscopically, the foci of pneumonia in lugs were voluminous or collapsed according to the nature and duration of the disease.
Harun ÖZER, H. Basri G ÜLCÜ
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Acta Orthopaedica et Traumatologica Turcica, 2021 Articular cartilage has a limited capacity for repair.We investigated the effect of mosaieplasty and fascia lata grafting method on the healing of full-thickness osteochondral defects in adult Turkish(Karaman) sheep.Double defects,ten milimeters wide by ...
Bulent Aksoy +7 more
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