Results 121 to 130 of about 231,893 (292)

Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis

open access: yesCell Proliferation, EarlyView.
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang   +16 more
wiley   +1 more source

Experimental joint immobilization in guinea pigs. Effects on the knee joint [PDF]

open access: yes
In young and adult guinea pigs, the aftermath experimentally induced by the immobilization of the knee joint in hyperextended forced position was studied. Joint immobilization which varied from one to nine weeks was attained by plaster.
Machado, F. F.   +3 more
core   +1 more source

Relationship Between Quantitative MRI Biomarkers and Patient-Reported Outcome Measures After Cartilage Repair Surgery: A Systematic Review. [PDF]

open access: yes, 2018
Background:Treatment of articular cartilage injuries remains a clinical challenge, and the optimal tools to monitor and predict clinical outcomes are unclear.
Cole, Brian J   +4 more
core   +1 more source

Equine experimental lameness induction models

open access: yesEquine Veterinary Education, EarlyView.
Summary Equine lameness due to musculoskeletal injury remains a common and significant cause of decreased performance. While our understanding and management of lameness have improved with advanced imaging, as well as diagnostic and therapeutic progression, a need for experimental equine models of lameness remains.
A. Dockery, B. Beasley, V. J. Moorman
wiley   +1 more source

Bone growth following demineralized bone matrix implantation requires angiogenesis [PDF]

open access: yes, 2016
Angiogenesis is required for endochondral ossification during development and fracture healing; however the exact mechanisms and temporal relationship between the two processes remains unclear.
Lam, Stephanie
core  

Effects of mechanical vibrations on chondrocytes in monolayer culture for regenerative cartilage

open access: yesMechanical Engineering Journal
Cartilage regenerative medicine requires time and effort to regenerate thick hyaline cartilage. In this study, we investigated the effects of mechanical vibrations on chondrocyte proliferation and cartilage matrix production to simplify the regenerative ...
Yura WATANABE, Toshihiko SHIRAISHI
doaj   +1 more source

New insights into Ituglanis (Siluriformes: Trichomycteridae) diversity in Bahia State, eastern Brazil: Description of a new species and conservation status reappraisal

open access: yesJournal of Fish Biology, EarlyView.
Abstract The northeastern Atlantic Forest of Brazil harbours a remarkable diversity of species of Trichomycteridae, many of which remain poorly understood. This study describes a new species of Ituglanis, endemic to the Ribeirão São Roque, a stream tributary of Rio Piabanha, an affluent of Rio Colônia basin, Bahia State, Brazil.
Paulo J. Vilardo   +2 more
wiley   +1 more source

Arthroscopic Knee Cartilage Repair With Covered Microfracture and Bone Marrow Concentrate

open access: yesArthroscopy Techniques, 2012
In recent years several single-stage cartilage repair approaches have been devised to treat focal cartilage lesions. These usually associate microfracture (MFX) and a coverage scaffold.
Antonio Gigante, M.D.   +4 more
doaj   +1 more source

Fatal Hemorrhagic Septicemia in Common Guitarfish (Rhinobatos rhinobatos) Caused by Photobacterium damselae Subsp. damselae in a Controlled Environment

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Elasmobranchs, including sharks and rays, are commonly housed in public aquariums due to their ecological significance and educational value. The common guitarfish (Rhinobatos rhinobatos), currently listed as ‘Critically Endangered’ by the IUCN, is particularly susceptible to population declines due to overfishing and bycatch.
Giorgia Bignami   +9 more
wiley   +1 more source

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