Results 11 to 20 of about 231,893 (292)

Hyaline cartilage differentiation of fibroblasts in regeneration and regenerative medicine.

Development, 2022
Amputation injuries in mammals are typically non-regenerative; however, joint regeneration is stimulated by BMP9 treatment, indicating the presence of latent articular chondrocyte progenitor cells.
Yu L, Lin YL, Yan M, Li T, Wu EY, Zimmel K, Qureshi O, Falck A, Sherman KM, Huggins SS, Hurtado DO, Suva LJ, Gaddy D, Cai J, Brunauer R, Dawson LA, Muneoka K.   +16 more
europepmc   +2 more sources

DDX5 inhibits hyaline cartilage fibrosis and degradation in osteoarthritis via alternative splicing and G-quadruplex unwinding. [PDF]

Nat Aging
Hyaline cartilage fibrosis is typically considered an end-stage pathology of osteoarthritis (OA), which results in changes to the extracellular matrix. However, the mechanism behind this is largely unclear.
Liu Q, Han M, Wu Z, Fu W, Ji J, Liang Q, Tan M, Zhai L, Gao J, Shi D, Shi D, Jiang Q, Sun Z, Lai Y, Xu Q, Sun Y.   +15 more
europepmc   +2 more sources

Regeneration of hyaline-like cartilage in situ with SOX9 stimulation of bone marrow-derived mesenchymal stem cells. [PDF]

PLoS ONE, 2017
Microfracture, a common procedure for treatment of cartilage injury, induces fibrocartilage repair by recruiting bone marrow derived mesenchymal stem cells (MSC) to the site of cartilage injury.
Xiaowei Zhang, Shili Wu, Ty Naccarato, Manan Prakash-Damani, Yuan Chou, Cong-Qiu Chu, Yong Zhu   +6 more
doaj   +2 more sources

Glycosaminoglycan, Antimicrobial Defence Molecule and Cytokine Appearance in Tracheal Hyaline Cartilage of Healthy Humans [PDF]

Journal of Functional Morphology and Kinesiology, 2022
Hyaline cartilage is an important tracheal structure, yet little is known about its molecular composition, complicating investigation of pathologies and replacement options.
Arina Deņisova, Māra Pilmane, Pavlo Fedirko   +2 more
doaj   +2 more sources

Transcriptomic and Proteomic Analyses Reveal the Potential Mode of Action of Chondrocyte Sheets in Hyaline Cartilage Regeneration. [PDF]

Int J Mol Sci, 2019
Chondrocyte sheet transplantation is a novel and promising approach to treating patients who have cartilage defects associated with osteoarthritis. Hyaline cartilage regeneration by autologous chondrocyte sheets has already been demonstrated in clinical ...
Toyoda E, Sato M, Takahashi T, Maehara M, Okada E, Wasai S, Watanabe M, Iijima H, Nonaka K, Kawaguchi Y.   +9 more
europepmc   +2 more sources

Mesenchymal Stem Cells in Oriented PLGA/ACECM Composite Scaffolds Enhance Structure-Specific Regeneration of Hyaline Cartilage in a Rabbit Model

Stem Cells International, 2018
Articular cartilage lacks a blood supply and nerves. Hence, articular cartilage regeneration remains a major challenge in orthopedics. Decellularized extracellular matrix- (ECM-) based strategies have recently received particular attention. The structure
Weimin Guo, Xifu Zheng, Weiguo Zhang, Mingxue Chen, Zhenyong Wang, Chunxiang Hao, Jingxiang Huang, Zhiguo Yuan, Yu Zhang, Mingjie Wang, Jiang Peng, Aiyuan Wang, Yu Wang, Xiang Sui, Wenjing Xu, Shuyun Liu, Shibi Lu, Quanyi Guo   +17 more
doaj   +2 more sources

Coculture of hWJMSCs and pACs in Oriented Scaffold Enhances Hyaline Cartilage Regeneration In Vitro. [PDF]

Stem Cells Int, 2019
Seed cells of articular cartilage tissue engineering face many obstacles in their application because of the dedifferentiation of chondrocytes or unstable chondrogenic differentiation status of pluripotent stem cells.
Zhang Y, Liu S, Guo W, Hao C, Wang M, Li X, Zhang X, Chen M, Wang Z, Sui X, Peng J, Wang Y, Lu S, Guo Q.   +13 more
europepmc   +2 more sources

Isolation and Characterisation of Major and Minor Collagens from Hyaline Cartilage of Hoki (Macruronus novaezelandiae). [PDF]

Mar Drugs, 2019
The composition and properties of collagen in teleost (bony fish) cartilage have never been studied. In this study, we aimed to identify and characterise all collagen species in the nasal cartilage of hoki (Macruronus novaezelandiae).
Cumming MH, Hall B, Hofman K.
europepmc   +2 more sources

Enhanced hyaline cartilage formation and continuous osteochondral regeneration via 3D-Printed heterogeneous hydrogel with multi-crosslinking inks [PDF]

Materials Today Bio
The unique gradient structure and complex composition of osteochondral tissue pose significant challenges in defect regeneration. Restoration of tissue heterogeneity while maintaining hyaline cartilage components has been a difficulty of an osteochondral
Zhonglian Wu, Hang Yao, Haidi Sun, Zehao Gu, Xu Hu, Jian Yang, Junli Shi, Haojun Yang, Jihang Dai, Hui Chong, Dong-An Wang, Liwei Lin, Wang Zhang   +12 more
doaj   +2 more sources

EXO/hydrogel system for sequential regulation of endogenous hyaline cartilage regeneration [PDF]

Materials Today Bio
Articular cartilage repair remains a clinically significant challenge due to its limited regenerative capacity and vulnerability to inflammation-induced damage and fibrocartilage formation.
Kang Wu, Rong Gong, Tianyu Gao, Yong Hu, Hongrui Wang, Weiye Zhang, Xiaoxu Wang, Yifan Wang, Ning Zhang   +8 more
doaj   +2 more sources