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Decellularized tissue engineered hyaline cartilage graft for articular cartilage repair
Biomaterials, 2020Articular cartilage repair has been a long-standing challenge in orthopaedic medicine due to the limited self-regenerative capability of cartilage tissue. Currently, cartilage lesions are often treated by microfracture or autologous chondrocyte implantation (ACI).
Nie, Xiaolei +5 more
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Collagens in Hyaline Cartilage
2016Collagens are the most abundant proteins in mammals and mostly incorporated into the extracellular matrix (ECM) where they form complex supramolecular structures additionally incorporating different non-collagenous components. The ECM of articular cartilage comprises the majority of the tissue volume and thus determines the properties of this unique ...
S. Grässel
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ACS Applied Materials and Interfaces, 2022
Hydrogel-based chondrocyte implantation presents a promising tissue engineering strategy for cartilage repair. However, the widely used elastic hydrogels usually restrict cell volume expansion and induce the dedifferentiation of encapsulated chondrocytes.
Yu Zhu +9 more
semanticscholar +1 more source
Hydrogel-based chondrocyte implantation presents a promising tissue engineering strategy for cartilage repair. However, the widely used elastic hydrogels usually restrict cell volume expansion and induce the dedifferentiation of encapsulated chondrocytes.
Yu Zhu +9 more
semanticscholar +1 more source
Isolation of Chondrons from Hyaline Cartilage
2022In native healthy hyaline cartilage, the chondrocytes are surrounded by a pericellular matrix that has a distinct composition and function compared to the hyaline cartilage extracellular matrix. The chondrocyte together with its pericellular matrix is called a chondron.
Korpershoek, Jasmijn V. +2 more
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ACS Biomaterials Science & Engineering, 2020
Hyaline cartilage regeneration remains clinically challenging. In this study, microbial transglutaminase was used to cross-link gelatin. The articular cartilage extracellular matrix (cECM), mainly comprising collagen type II and glycosaminoglycans (GAGs),
Ching-Cheng Tsai +5 more
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Hyaline cartilage regeneration remains clinically challenging. In this study, microbial transglutaminase was used to cross-link gelatin. The articular cartilage extracellular matrix (cECM), mainly comprising collagen type II and glycosaminoglycans (GAGs),
Ching-Cheng Tsai +5 more
semanticscholar +1 more source
Orthopaedics and Trauma, 2009
Abstract Hyaline articular cartilage forms an important component of synovial joints, the integrity of which is crucial for normal function. Knowledge of its composition and dynamics is important for a better understanding of joint diseases pathophysiology and management.
Ehab Kheir, David Shaw
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Abstract Hyaline articular cartilage forms an important component of synovial joints, the integrity of which is crucial for normal function. Knowledge of its composition and dynamics is important for a better understanding of joint diseases pathophysiology and management.
Ehab Kheir, David Shaw
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Hyaline cartilage changes in diastrophic dwarfism
Virchows Archiv A Pathological Anatomy and Histology, 1978Hyaline cartilage of the talus of a diastrophic dwarf was studied by light and transmission electron microscopy before and after proteoglycan extraction or digestion, glycogen digestion, and enzyme marking. The nuclei of the chondrocytes were as a rule large and round and the cytoplasm contained large vacuoles.
M, Scheck, J, Parker, D, Daentl
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Precision of Hyaline Cartilage Thickness Measurements
Acta Radiologica, 1992Measurement of cartilage thickness in vivo is an important indicator of the status of a joint as the various degenerative and inflammatory arthritides directly affect the condition of the cartilage. In order to assess the precision of thickness measurements of hyaline articular cartilage, we undertook a pilot study using MR imaging, plain radiography,
K, Jonsson +4 more
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American Journal of Sports Medicine, 2020
Background: Microfracture or bone marrow stimulation (BMS) is often the first choice for clinical treatment of cartilage injuries; however, fibrocartilage, not pure hyaline cartilage, has been reported because of the development of fibrosis in the repair
Hajime Utsunomiya +12 more
semanticscholar +1 more source
Background: Microfracture or bone marrow stimulation (BMS) is often the first choice for clinical treatment of cartilage injuries; however, fibrocartilage, not pure hyaline cartilage, has been reported because of the development of fibrosis in the repair
Hajime Utsunomiya +12 more
semanticscholar +1 more source
Extracellular Matrix Scaffold Using Decellularized Cartilage for Hyaline Cartilage Regeneration
2021The repair of osteochondral defects is among the top ten medical needs of humans in the 21st centuries with many countries facing rapidly aging population involved with osteoarthritis as a major contributor to global disease burden. Tissue engineering methods have offered new windows of hope to treat such disorders and disabilities.
Seyed Mostafa, Monzavi +3 more
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