Results 101 to 110 of about 272,669 (349)
The Detection of Nanoscale Membrane Bending with Polarized Localization Microscopy [PDF]
arXiv, 2017 The curvature of biological membranes at the nanometer scale is critically important for vesicle trafficking, organelle morphology, and disease propagation. This manuscript reports the development of Polarized Localization Microscopy (PLM), a pointillist optical imaging technique for the detection of nanoscale membrane curvature in correlation with ...
arxiv
The Prognostic Significance of Tumoral Melanosis
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Background Tumoral melanosis (TM) is a histological term to describe a nodular aggregation of macrophages containing melanin pigment (melanophages) that is devoid of viable melanocytes. It is most often identified in skin, where it may be appreciated clinically as a pigmented lesion; however, it can also be found in other organs such as lymph ...
Alison J. Potter +7 more
wiley +1 more source
Myocardial infarction and subsequent pregnancy
Arquivos Brasileiros de Cardiologia, 2000 We report the case of a 40-year-old woman with 2 previous myocardial infarctions, revascularization surgery, and an ongoing pregnancy complicated with preeclampsia and fetal hypoxia.
Tedoldi Citânia Lúcia +1 more
doaj
Membrane-protein interactions hold the key to understanding amyloid formation [PDF]
J. Phys. Chem. Letters 5, 633-635 (2014), 2014 In this perspective we describe the critical role membranes play in modulating the structures of the Amyloid Precursor Proteins to produce the peptides involved in the Alzheimer's disease. Some of the key concepts related to protein aggregation including the potential role of the excited states of monomers in initiating protein aggregation are ...
arxiv
The Lorentz Force on Ions in Membrane Channels of Neurons as a Mechanism for Transcranial Static Magnetic Stimulation [PDF]
arXiv, 2020 Transcranial static magnetic stimulation is a novel noninvasive method of reduction of the cortical excitability in certain neurological diseases that, unlike ordinary transcranial magnetic stimulation, makes use of static magnetic fields generated by permanent magnets.
arxiv
Frequency-Rank Correlations of Rhodopsin Mutations with Tuned Hydropathic Roughness Based on Self-Organized Criticality [PDF]
, 2012 The behavior of disease-linked mutations of membrane proteins is especially simple in rhodopsin, where they are well-studied, as they are responsible for retinitis pigmentosa, RP (retinal degeneration). Here we show that the frequency of occurrence of single RP mutations is strongly influenced by their posttranslational survival rates, and that this ...
arxiv +1 more source
Membrane Interactions in Alzheimer`s Treatment Strategies with Multitarget Molecules [PDF]
Addressing Alzheimer's disease (AD) requires innovative strategies beyond current single-target drugs. This Letter to the Editor suggests that multitarget molecules, especially those targeting neuronal membrane protection, could offer a comprehensive approach to AD therapy, advocating for further research into their mechanisms and therapeutic potential.
arxiv +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background MicroRNAs, a class of small noncoding RNAs, serve as post‐transcriptional regulators of gene expression and are present in a stable and quantifiable form in biological fluids. MicroRNAs may influence intra‐articular responses and the course of disease, but very little is known about their temporal changes in osteoarthritis ...
Marie Walters +10 more
wiley +1 more source
Doped graphene oxide functionalization strategy for synthesis of nanocomposite membranes: electrospun coatings in biomedical field application [PDF]
arXiv, 2020 An electrospun membrane for vascular stent coating made of 2-methacryloyloxyethyl phosphorylcholine and butyl methacrylate copolymer (MPC-co-BMA), also known as (PMB), reinforced with functionalized and nitrogen doped reduced graphene oxide (f-NrGO) is presented.
arxiv
Osteochondrosis in horses: An overview of genetic and other factors
Equine Veterinary Journal, EarlyView.Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez +2 more
wiley +1 more source