Results 1 to 10 of about 647,511 (278)

Altered surfactant homeostasis and recurrent respiratory failure secondary to TTF-1 nuclear targeting defect

open access: yesRespiratory Research, 2011
Background Mutations of genes affecting surfactant homeostasis, such as SFTPB, SFTPC and ABCA3, lead to diffuse lung disease in neonates and children. Haploinsufficiency of NKX2.1, the gene encoding the thyroid transcription factor-1 (TTF-1) - critical ...
Carnielli Virgilio P   +8 more
doaj   +1 more source

A Comparison of the Effect of Beractant (Beracsurf) and Proctant Alpha (Curosurf) in Neonatal Respiratory Distress: A Randomized Controlled Trial [PDF]

open access: yesIranian Journal of Medical Sciences
Background: Surfactant treatment has revolutionized the management of respiratory distress syndrome (RDS) in preterm infants. The present study compared the effectiveness and adverse effects of two natural surfactants, Beracsurf and Curosurf, in ...
Khadijeh Sadat Najib   +3 more
doaj   +1 more source

Porcine versus bovine surfactant therapy for RDS in preterm neonates: pragmatic meta-analysis and review of physiopathological plausibility of the effects on extra-pulmonary outcomes

open access: yesRespiratory Research, 2020
Background While porcine seems to be superior to bovine surfactants in terms of respiratory outcomes, it is unclear if a surfactant can improve extra-pulmonary outcomes in preterm neonates with respiratory distress syndrome and if there is any ...
Silvia Foligno, Daniele De Luca
doaj   +1 more source

Surfactant spreading on liquid films in the Stokes regime

open access: yesAIP Advances, 2022
Characterizing the spreading of surfactants on the surface of a liquid film is central to our understanding of natural and technological processes ranging from cell propulsion and drug delivery in pulmonary airways to cleaning food processing surfaces ...
Jiakai Lu   +3 more
doaj   +1 more source

Pulmonary Surfactant and Drug Delivery: An Interface-Assisted Carrier to Deliver Surfactant Protein SP-D Into the Airways

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
This work is focused on the potential use of pulmonary surfactant to deliver full-length recombinant human surfactant protein SP-D (rhSP-D) using the respiratory air-liquid interface as a shuttle.
Cristina García-Mouton   +5 more
doaj   +1 more source

EXOGENOUS SURFACTANTS OF NATURAL ORIGIN IN THE TREATMENT OF RESPIRATORY DISTRESS SYNDROME - COMPARATIVE COMPOSITION, BIOPHYSICAL PROPERTIES AND CLINICAL EFFECTIVENESS

open access: yesНеонатологія, хірургія та перинатальна медицина, 2020
Respiratory distress syndrome (RDS) remains an important cause of morbidity and mortality in premature infants in Ukraine and around the world. Since the determination of surfactant deficiency as the main cause of this disease, significant progress has ...
D.О. Dobryanskyy
doaj   +1 more source

Timing of initial surfactant treatment in very low birth weight newborns [PDF]

open access: yesEinstein (São Paulo), 2010
Objective: To correlate the timing of treatment using exogenous surfactant with the main variables related to respiratory distress syndrome or prematurity.
Celso Moura Rebello   +3 more
doaj   +4 more sources

Surfactant for pulmonary haemorrhage in neonates [PDF]

open access: yesCochrane Database of Systematic Reviews, 2008
In the 1960s and 1970s, pulmonary haemorrhage (PH) occurred mainly in full-term infants with pre-existing illness with an incidence of 1.3 per 1000 live births. Risk factors for PH included severity of illness, intrauterine growth restriction, patent ductus arteriosus (PDA), coagulopathy and the need for assisted ventilation. Presently, PH occurs in 3%
Abdul, Aziz, Arne, Ohlsson
openaire   +4 more sources

Pulmonary Surfactant Preparations and Surfactant Therapy for ARDS in Surgical Intensive Care (a Literature Review)

open access: yesКреативная хирургия и онкология, 2019
Introduction. Despite the fact that clinical studies of pulmonary surfactants conducted over many years have demonstrated their efficacy for the treatment of acute respiratory distress syndrome (ARDS) which led to their approval for use inRussia ...
O. A. Rosenberg
doaj   +1 more source

Ionic Surface Active Compounds in Atmospheric Aerosols

open access: yesThe Scientific World Journal, 2002
Surfactants in the atmosphere have several potential roles in atmospheric chemistry. They can form films on aqueous surfaces, which lowers the surface tension and possibly delays water evaporation and gaseous transportation across the aqueous interface ...
Jariya Sukhapan, Peter Brimblecombe
doaj   +1 more source

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