Results 1 to 10 of about 592,819 (238)
Frontiers in Pharmacology, 2021 Lung alveolar type-II (AT-II) cells produce pulmonary surfactant (PS), consisting of proteins and lipids. The lipids in PS are primarily responsible for reducing the air-fluid surface tension inside the alveoli of the lungs and to prevent atelectasis ...
Shengguang Wang +5 more
doaj +3 more sources
iScience, 2022 Summary: Steroid-sensitive nephrotic syndrome (SSNS) in childhood is usually due to minimal change disease (MCD). Unlike many glomerular conditions, SSNS/MCD is commonly precipitated by respiratory infections. Of interest, pulmonary inflammation releases
Gabriel Cara-Fuentes +9 more
doaj +1 more source
Synthetic lung surfactants containing SP-B and SP-C peptides plus novel phospholipase-resistant lipids or glycerophospholipids [PDF]
PeerJ, 2016 Background This study examines the biophysical and preclinical pulmonary activity of synthetic lung surfactants containing novel phospholipase-resistant phosphonolipids or synthetic glycerophospholipids combined with Super Mini-B (S-MB) DATK and/or SP ...
Robert H. Notter +5 more
doaj +2 more sources
Interfacial mechanisms for stability of surfactant-laden films. [PDF]
PLoS ONE, 2017 Thin liquid films are central to everyday life. They are ubiquitous in modern technology (pharmaceuticals, coatings), consumer products (foams, emulsions) and also serve vital biological functions (tear film of the eye, pulmonary surfactants in the lung).
M Saad Bhamla +4 more
doaj +1 more source
A recipe for a good clinical pulmonary surfactant
Biomedical Journal, 2022 The lives of thousands premature babies have been saved along the last thirty years thanks to the establishment and consolidation of pulmonary surfactant replacement therapies (SRT).
Jesús Pérez-Gil
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Journal of Applied Physiology, 1982 Pulmonary surfactant reduces the surface tension of the alveolar air-liquid interface, thereby providing mechanical stability and preventing alveolar atelectasis. More than 50% of surfactant is dipalmitoyl phosphatidylcholine, a material that is capable of reducing the surface tension of the alveolar interface to uniquely low values.
P, Gutkowski, W, Lejman
openaire +4 more sources
Jornal de Pediatria, 2001 OBJETIVO: apresentar a evolução clínica de recém-nascido portador de insuficiência respiratória grave neonatal secundária à Sindrome de Aspiração Meconial tratado por Circulação Extracorpórea por Membrana, ou, conforme o termo consagrado em língua ...
João Gilberto Maksoud-Filho +6 more
doaj +1 more source
Insights Gained Into the Treatment of COVID19 by Pulmonary Surfactant and Its Components
Frontiers in Immunology, 2022 Pulmonary surfactant constitutes an important barrier that pathogens must cross to gain access to the rest of the organism via the respiratory surface.
Dan Li +6 more
doaj +1 more source
Общая реаниматология, 2007 Objective: to study the effects of the surfactants Surfactant-BL and Curosurf on pulmonary oxygenizing properties in preterm neonatal infants with respiratory distress syndrome (RDS). The studies were performed in 81 preterm neonates with severe RDS. For
S. A. Perepelitsa +2 more
doaj +1 more source
Respiratory Research, 2011 Background Mutations of genes affecting surfactant homeostasis, such as SFTPB, SFTPC and ABCA3, lead to diffuse lung disease in neonates and children. Haploinsufficiency of NKX2.1, the gene encoding the thyroid transcription factor-1 (TTF-1) - critical ...
Carnielli Virgilio P +8 more
doaj +1 more source