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The Role of Pulmonary Surfactants in the Treatment of Acute Respiratory Distress Syndrome in COVID-19 [PDF]

open access: yesFrontiers in Pharmacology, 2021
Lung alveolar type-II (AT-II) cells produce pulmonary surfactant (PS), consisting of proteins and lipids. The lipids in PS are primarily responsible for reducing the air-fluid surface tension inside the alveoli of the lungs and to prevent atelectasis ...
Shengguang Wang   +2 more
exaly   +5 more sources

Pulmonary Surfactants: a New Therapeutic Target in Asthma. [PDF]

open access: yesCurr Allergy Asthma Rep, 2020
PURPOSE OF REVIEW: Lung tissues are highly susceptible to airway inflammation as they are inevitably exposed to inhaled pathogens and allergens. In the lungs, clearance of infectious agents and regulation of inflammatory responses are important for the ...
Choi Y, Jang J, Park HS.
europepmc   +3 more sources

Pulmonary surfactants and the respiratory-renal connection in steroid-sensitive nephrotic syndrome of childhood [PDF]

open access: yesIScience, 2022
Summary: Steroid-sensitive nephrotic syndrome (SSNS) in childhood is usually due to minimal change disease (MCD). Unlike many glomerular conditions, SSNS/MCD is commonly precipitated by respiratory infections. Of interest, pulmonary inflammation releases
Gabriel Cara-Fuentes   +2 more
exaly   +4 more sources

Effects of different pulmonary surfactants in the prevention of postoperative intraabdominal adhesion formation [PDF]

open access: yesJournal of Pediatric Surgery, 2012
Background: After abdominal surgery, the formation of postoperative adhesion is a serious problem. The aim of the study is to evaluate the efficacy of 2 different pulmonary surfactants, poractant and beractant, on adhesion prevention in an experimental ...
Arzu Pampal   +2 more
exaly   +4 more sources

Kinematic viscosity of therapeutic pulmonary surfactants with added polymers

open access: yesBiochimica Et Biophysica Acta - Biomembranes, 2009
The addition of various polymers to pulmonary surfactants improves surface activity in experiments both in vitro and in vivo. Although the viscosity of surfactants has been investigated, the viscosity of surfactant polymer mixtures has not. In this study,
Karen W Lu   +2 more
exaly   +3 more sources

Strategies to Enhance Drug Absorption via Nasal and Pulmonary Routes

open access: yesPharmaceutics, 2019
New therapeutic agents such as proteins, peptides, and nucleic acid-based agents are being developed every year, making it vital to find a non-invasive route such as nasal or pulmonary for their administration.
Maliheh Ghadiri   +2 more
doaj   +3 more sources

A recipe for a good clinical pulmonary surfactant

open access: yesBiomedical Journal, 2022
The lives of thousands premature babies have been saved along the last thirty years thanks to the establishment and consolidation of pulmonary surfactant replacement therapies (SRT).
Jesús Pérez-Gil
doaj   +2 more sources

Comparative study of clinical pulmonary surfactants using atomic force microscopy

open access: yesBiochimica et Biophysica Acta, 2011
Clinical pulmonary surfactant is routinely used to treat premature newborns with respiratory distress syndrome, and has shown great potential in alleviating a number of neonatal and adult respiratory diseases.
Neal, Charles R.   +9 more
core   +2 more sources

Pulmonary Surfactants for Acute and Chronic Lung Diseases (Part I)

open access: yesОбщая реаниматология, 2014
Part 1 of the review gives information on the composition and properties of a pulmonary surfactant and quantitative and qual itative impairments in the pulmonary surfactant system in different neonatal and adult abnormalities and describes the ...
O. A. Rozenberg
doaj   +3 more sources

Effects of Exogenous Surfactants on the Parameters of Blood Gas Composition in Neonatal Respiratory Distress Syndrome

open access: yesОбщая реаниматология, 2007
Objective: to study the effects of the surfactants Surfactant-BL and Curosurf on pulmonary oxygenizing properties in preterm neonatal infants with respiratory distress syndrome (RDS). The studies were performed in 81 preterm neonates with severe RDS. For
S. A. Perepelitsa   +2 more
doaj   +2 more sources

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