Results 31 to 40 of about 592,819 (238)

In vitro characterization and in vivo comparison of the pulmonary outcomes of Poractant alfa and Calsurf in ventilated preterm rabbits.

PLoS ONE, 2020
Poractant alfa and Calsurf are two natural surfactants widely used in China for the treatment of neonatal respiratory distress syndrome, which are extracted from porcine and calf lungs, respectively.
Xiaojing Guo, Siwei Luo, Davide Amidani, Claudio Rivetti, Giuseppe Pieraccini, Barbara Pioselli, Silvia Catinella, Xabi Murgia, Fabrizio Salomone, Yaling Xu, Ying Dong, Bo Sun   +11 more
doaj   +1 more source

Effect of surfactants on liquid side mass transfer coefficients [PDF]

, 2005
In the present paper, the effect of liquid properties (surfactants) on bubble generation phenomenon, interfacial area and liquid side mass transfer coefficient was investigated.
Hebrard, Gilles, Loubière, Karine, Roustan, Michel, Mietton-Peuchot, Martine, Painmanakul, Pisut   +4 more
core   +1 more source

Procedural success and safety of a standardized less invasive surfactant administration protocol using fentanyl premedication and video laryngoscopy in preterm infants <32 weeks’ gestation

Frontiers in Pediatrics
BackgroundLess Invasive Surfactant Administration (LISA) has been established for treating respiratory distress syndrome (RDS) in preterm infants, but the impact of pharmacological analgesia or video laryngoscopy on procedural success and safety remains ...
Mircea-Horia Popa-Todirenchi, Benedikt Bubl, Fabian Keller, Marta Busso, Sophie Jaisli, Lisa Marie Bünte, Marc-Alexander Oestreich, Marc-Alexander Oestreich, André Kidszun   +8 more
doaj   +1 more source

Budesonide/formoterol enhances the expression of pro Surfactant Protein-B in lungs of COPD patients. [PDF]

PLoS ONE, 2013
Pulmonary surfactants are essential components of lung homeostasis. In chronic obstructive pulmonary disease (COPD), surfactant expression decreases in lungs whereas, there is a paradoxical increase in protein expression in plasma.
Soo Jung Um, Stephen Lam, Harvey Coxson, Shu Fan Paul Man, Don D Sin   +4 more
doaj   +1 more source

YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1

iScience, 2021
Summary: Ventilation is dependent upon pulmonary alveoli lined by two major epithelial cell types, alveolar type-1 (AT1) and 2 (AT2) cells. AT1 cells mediate gas exchange while AT2 cells synthesize and secrete pulmonary surfactants and serve as ...
Jason J. Gokey, John Snowball, Anusha Sridharan, Parvathi Sudha, Joseph A. Kitzmiller, Yan Xu, Jeffrey A. Whitsett   +6 more
doaj   +1 more source

COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation

Mediators of Inflammation, 2021
Causes of mortality from COVID-19 include respiratory failure, heart failure, and sepsis/multiorgan failure. TLR4 is an innate immune receptor on the cell surface that recognizes pathogen-associated molecular patterns (PAMPs) including viral proteins and
Mohamed M. Aboudounya, Richard J. Heads
doaj   +1 more source

Unraveling the enigma: The emerging significance of pulmonary surfactant proteins in predicting, diagnosing, and managing COVID‐19

Immunity, Inflammation and Disease
Background Severe cases of COVID‐19 often lead to the development of acute respiratory syndrome, a critical condition believed to be caused by the harmful effects of SARS‐CoV‐2 on type II alveolar cells.
Mohammad Navid Bastani, Shahram Jalilian
doaj   +1 more source

A case of autoimmune pulmonary alveolar proteinosis with severe respiratory failure treated with segmental lung lavage and oral statin therapy

Respiratory Medicine Case Reports, 2022
Pulmonary alveolar proteinosis (PAP) is a diffuse lung disease characterized by the accumulation of alveolar surfactants due to dysfunction of granulocyte-macrophage colony-stimulating factor-dependent cholesterol clearance.
Tomotsugu Takano, Keisuke Takeda, Satoshi Nakamura, Genta Akiyama, Nobuhisa Ando, Masashi Komori   +5 more
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Polymeric surfactants

, 2022
S.246-249The contribution gives an overview over polymeric surfactants that are suited to act as micellar polymers in aqueous media. The various polymer types are presented, and the characteristic property profiles distinguishing the classes are ...
Laschewsky, A.
core   +1 more source