Results 51 to 60 of about 647,511 (278)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

Polymeric surfactants: Novel agents with exceptional properties

open access: yes, 2022
S.88-102This article presents recent progress in the field of polymeric surfactants made of permanently amphiphilic block copolymers or of stimulus-sensitive ones.
Garnier, S.   +2 more
core  

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

open access: yesAdvanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim   +12 more
wiley   +1 more source

Polymeric surfactants

open access: yes, 2022
S.246-249The contribution gives an overview over polymeric surfactants that are suited to act as micellar polymers in aqueous media. The various polymer types are presented, and the characteristic property profiles distinguishing the classes are ...
Laschewsky, A.
core   +1 more source

Comparison of Two Natural Surfactants for Pulmonary Hemorrhage in Very Low-Birth-Weight Infants: A Randomized Controlled Trial

open access: yes, 2015
Objective To compare the efficacy of two natural surfactants for pulmonary hemorrhage in very low-birth-weight (VLBW ...
Dilmen, Ugur   +3 more
core   +1 more source

A Huaxian Formula Nanoformulation Confers Protection Against Acute Radiation‐Induced Lung Injury by Targeting Ferroptosis

open access: yesAdvanced Science, EarlyView.
An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Li Quan   +11 more
wiley   +1 more source

The Scientific Network of Surfactants: Structural Analysis [PDF]

open access: yes, 2006
The scientific network of the surfactants and related subjects has been analyzed with the CoPalRed© knowledge system. The actors studied have been countries, research centers and laboratories, researchers, and journals.
Ruiz-Baños, Rosario   +2 more
core   +2 more sources

Pulmonary Surfactants for Acute and Chronic Lung Diseases (Part II)

open access: yesОбщая реаниматология, 2014
Part 2 of the review considers the problem of surfactant therapy for acute respiratory distress syndrome (ARDS) in adults and young and old children. It gives information on the results of surfactant therapy and prevention of ARDS in patients with severe
O. A. Rozenberg
doaj   +1 more source

Microfluidic Gratings for X‐Ray Phase Contrast Imaging

open access: yesAdvanced Science, EarlyView.
This work establishes a new protocol for the fabrication of X‐ray gratings that exploits the advantages of microfluidics and enables a more inexpensive, faster, and scalable production process. These X‐ray devices are fundamental for implementing X‐ray phase contrast imaging (XPCI) in laboratory and clinical settings, yet their costly and complex ...
Alessandro Rossi   +10 more
wiley   +1 more source

Exogenous surfactant for lung contusion causing ARDS: A systematic review of clinical and experimental reports

open access: yesThe Clinical Respiratory Journal
This systematic review aimed to summarize the available data on the treatment of pulmonary contusions with exogenous surfactants, determine whether this treatment benefits patients with severe pulmonary contusions, and evaluate the optimal type of ...
Tomáš Merkl   +7 more
doaj   +1 more source

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