Results 1 to 10 of about 74,060 (177)
Pulmonary surfactant and prostaglandin E2 in airway smooth muscle relaxation of human and male guinea pigs [PDF]
Physiological ReportsPulmonary surfactant serves as a barrier to respiratory epithelium but can also regulate airway smooth muscle (ASM) tone. Surfactant (SF) relaxes contracted ASM, similar to β2‐agonists, anticholinergics, nitric oxide, and prostanoids. The exact mechanism
J. Hanusrichterova +14 more
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In vivo clearance of surfactant lipids during acute pulmonary inflammation. [PDF]
Respiratory Research, 2004 Background A decrease in pulmonary surfactant has been suggested to contribute to the lung dysfunction associated with pulmonary inflammation. A number of studies have implicated surfactant clearance as a possible mechanism for altered pool sizes.
Wright Jo Rae, Malloy Jaret L
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Surfactant protein a in cystic fibrosis: supratrimeric structure and pulmonary outcome. [PDF]
, 2012 The state of oligomerization of surfactant associated protein-A (SP-A) monomers differs between individuals. This likely affects SP-A's functional properties and could thereby influence clinical status in patients with lung diseases.
Ballmann, Manfred +7 more
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Pulmonary surfactant system [PDF]
Eurasian Journal of Veterinary SciencesPulmonary surfactant, a phospholipid-protein complex that lines the alveoli and small airways of the lungs, is secreted by type ll alveolar epithelial cells. Recognized functions of surfactant are (1) maintaining proper humidity of the alveolar wall; (2)
Zafer Durgun, Ercan Keskin
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Frontiers in Immunology, 2021 Pulmonary surfactant is a complex and highly surface-active material. It covers the alveolar epithelium and consists of 90% lipids and 10% proteins. Pulmonary surfactant lipids together with pulmonary surfactant proteins facilitate breathing by reducing ...
Jianjian Ji +7 more
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Insights Gained Into the Treatment of COVID19 by Pulmonary Surfactant and Its Components
Frontiers in Immunology, 2022 Pulmonary surfactant constitutes an important barrier that pathogens must cross to gain access to the rest of the organism via the respiratory surface.
Dan Li +6 more
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European Respiratory Review, 2021 Pulmonary surfactant is a crucial and dynamic lung structure whose primary functions are to reduce alveolar surface tension and facilitate breathing.
Nadia Milad, Mathieu C. Morissette
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Effect of Nebulized Bovine Surfactant for Experimental Otitis Media with Effusion [PDF]
Clinical and Experimental Otorhinolaryngology, 2010 ObjectivesIn this study, we evaluated the efficacy of nebulized bovine pulmonary surfactant on experimentally induced otitis media with effusion (OME) in guinea pigs.MethodsTwenty guinea pigs were divided into three groups.
Chul Ho Jang +5 more
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Genetic disorders of the surfactant system: focus on adult disease
European Respiratory Review, 2021 Genes involved in the production of pulmonary surfactant are crucial for the development and maintenance of healthy lungs. Germline mutations in surfactant-related genes cause a spectrum of severe monogenic pulmonary diseases in patients of all ages. The
Coline H.M. van Moorsel +2 more
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Stem Cell Research, 2021 Surfactant dysfunction is a genetically heterogeneous pulmonary disease that causes dyspnea. ATP binding cassette protein transporter subunit A3 (ABCA3) is the main pathogenic gene of pulmonary surfactant dysfunction.
Xiaojuan Yin +9 more
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