Results 21 to 30 of about 74,178 (294)

Pulmonary surfactant

open access: yesJournal of Applied Physiology, 1982
Pulmonary surfactant reduces the surface tension of the alveolar air-liquid interface, thereby providing mechanical stability and preventing alveolar atelectasis. More than 50% of surfactant is dipalmitoyl phosphatidylcholine, a material that is capable of reducing the surface tension of the alveolar interface to uniquely low values.
P, Gutkowski, W, Lejman
openaire   +4 more sources

Nanocarrier lipid composition modulates the impact of pulmonary surfactant protein B (SP-B) on cellular delivery of siRNA [PDF]

open access: yes, 2019
Two decades since the discovery of the RNA interference (RNAi) pathway, we are now witnessing the approval of the first RNAi-based treatments with small interfering RNA (siRNA) drugs. Nevertheless, the widespread use of siRNA is limited by various extra-
De Backer, Lynn   +7 more
core   +1 more source

Pulmonary Surfactants for Acute and Chronic Lung Diseases (Part I)

open access: yesОбщая реаниматология, 2014
Part 1 of the review gives information on the composition and properties of a pulmonary surfactant and quantitative and qual itative impairments in the pulmonary surfactant system in different neonatal and adult abnormalities and describes the ...
O. A. Rozenberg
doaj   +1 more source

Restoration of surfactant activity by polymyxin B in lipopolysaccharide-potentiated injury of immature rabbit lungs

open access: yesScientific Reports, 2021
During postnatal adaptation pulmonary surfactant may be inactivated by lipopolysaccharide (LPS). We evaluated the effect of surfactant therapy in combination with antibiotic polymyxin B (PxB) in double-hit model of neonatal lung injury.
Andrea Calkovska   +2 more
doaj   +1 more source

Short-term Outcome of Pulmonary Hemorrhage in Very-Low-Birth-Weight Preterm Infants

open access: yesPediatrics and Neonatology, 2013
Severe pulmonary hemorrhage is a serious complication with a high mortality rate in preterm infants with respiratory distress syndrome (RDS) after surfactant therapy.
Ting-An Yen   +5 more
doaj   +1 more source

Methane Inhalation Protects Against Lung Ischemia-Reperfusion Injury in Rats by Regulating Pulmonary Surfactant via the Nrf2 Pathway

open access: yesFrontiers in Physiology, 2021
Methane (CH4) exerted protective effects against lung ischemia-reperfusion (I/R) injury, but the mechanism remains unclear, especially the role of pulmonary surfactant.
Bing Zhang   +7 more
doaj   +1 more source

Changes in the Activity of the Pulmonary Surfactant after Contact with Bentonite Nanoclay Particles

open access: yesChemical Engineering Transactions, 2012
Nanoclays are used as fillers in the production of polymer nanocomposites. They contribute to improving the physical, heat and resistance properties of nanocomposites.
D. Kondej, T. Sosnowski
doaj   +1 more source

Interfacial Reactions of Ozone with Surfactant Protein B in a Model Lung Surfactant System [PDF]

open access: yes, 2010
Oxidative stresses from irritants such as hydrogen peroxide and ozone (O_3) can cause dysfunction of the pulmonary surfactant (PS) layer in the human lung, resulting in chronic diseases of the respiratory tract.
Beauchamp, J. L.   +9 more
core   +2 more sources

Single Versus Multiple Doses of Surfactant Treatment in Preterm Infants

open access: yesJournal of Pediatric Research, 2020
Aim:Exogenous surfactant may be needed not only for Respiratory Distress syndrome (RDS) treatment; but also, in the management of other pulmonary diseases of infants.
Betül Siyah Bilgin   +5 more
doaj   +1 more source

Recent advances in understanding idiopathic pulmonary fibrosis [PDF]

open access: yes, 2016
Despite major research efforts leading to the recent approval of pirfenidone and nintedanib, the dismal prognosis of idiopathic pulmonary fibrosis (IPF) remains unchanged.
Daccord, C, Maher, TM
core   +3 more sources

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