Pulmonary Surfactants for Acute and Chronic Lung Diseases (Part I)
Part 1 of the review gives information on the composition and properties of a pulmonary surfactant and quantitative and qual itative impairments in the pulmonary surfactant system in different neonatal and adult abnormalities and describes the ...
O. A. Rozenberg
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During the COVID-19 pandemic, the treatment of pulmonary fungal infection faced noteworthy challenges. Amphotericin B has shown promising therapeutic effects as an inhalation treatment for pulmonary fungal infections, especially those associated with the
Juan Wang +3 more
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Surfactant protein SP-B: one ring to rule the molecular and biophysical mechanisms of the pulmonary surfactant system. [PDF]
Pulmonary surfactant is a lipid/protein complex crucial to maintain mammalian lungs open, as it facilitates breathing mechanics through a dramatic reduction of surface tension at the air–liquid interface.
Alonso A, Olmeda B, Pérez-Gil J.
europepmc +2 more sources
Surfactant protein a in cystic fibrosis: supratrimeric structure and pulmonary outcome. [PDF]
The state of oligomerization of surfactant associated protein-A (SP-A) monomers differs between individuals. This likely affects SP-A's functional properties and could thereby influence clinical status in patients with lung diseases.
Karl Paul +15 more
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During postnatal adaptation pulmonary surfactant may be inactivated by lipopolysaccharide (LPS). We evaluated the effect of surfactant therapy in combination with antibiotic polymyxin B (PxB) in double-hit model of neonatal lung injury.
Andrea Calkovska +2 more
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Surfactant for pulmonary haemorrhage in neonates [PDF]
In the 1960s and 1970s, pulmonary haemorrhage (PH) occurred mainly in full-term infants with pre-existing illness with an incidence of 1.3 per 1000 live births. Risk factors for PH included severity of illness, intrauterine growth restriction, patent ductus arteriosus (PDA), coagulopathy and the need for assisted ventilation. Presently, PH occurs in 3%
Abdul, Aziz, Arne, Ohlsson
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The detection of surfactant proteins A, B, C and D in the human brain and their regulation in cerebral infarction, autoimmune conditions and infections of the CNS [PDF]
Surfactant proteins (SP) have been studied intensively in the respiratory system. Surfactant protein A and surfactant protein D are proteins belonging to the family of collectins each playing a major role in the innate immune system.
Dankwart Stiller +16 more
core +2 more sources
Changes in the Activity of the Pulmonary Surfactant after Contact with Bentonite Nanoclay Particles
Nanoclays are used as fillers in the production of polymer nanocomposites. They contribute to improving the physical, heat and resistance properties of nanocomposites.
D. Kondej, T. Sosnowski
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Analysis of lung surfactant phosphatidylcholine metabolism in transgenic mice using stable isotopes [PDF]
Stable isotope labelling of lipid precursors coupled with mass spectrometry-based lipidomic analyses and determination of isotope enrichment in substrate, intermediate and product pools provide the parameters needed to determine absolute flux rates ...
Grielof Koster +9 more
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Short-term Outcome of Pulmonary Hemorrhage in Very-Low-Birth-Weight Preterm Infants
Severe pulmonary hemorrhage is a serious complication with a high mortality rate in preterm infants with respiratory distress syndrome (RDS) after surfactant therapy.
Ting-An Yen +5 more
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