Lung surfactant alterations in pulmonary thromboembolism
European Journal of Medical Research, 2009 Beside neonatal respiratory distress syndrome, secondary surfactant deficiency may occur in patients with mature lungs. Recent studies revealed quantitative and qualitative changes of lung surfactant in pulmonary thromboembolism (PTE) concerning the ...
Calkovska A, Mokra D, Calkovsky V
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Gene Therapy Potential for Genetic Disorders of Surfactant Dysfunction
Frontiers in Genome Editing, 2022 Pulmonary surfactant is critically important to prevent atelectasis by lowering the surface tension of the alveolar lining liquid. While respiratory distress syndrome (RDS) is common in premature infants, severe RDS in term and late preterm infants ...
Ashley L. Cooney +6 more
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Surfactant function in neonates with respiratory distress syndrome [PDF]
, 1998 The function of pulmonary surfactant of a group of 14 preterm neonates (birth weight 907 +/- 60 g) who suffered from severe respiratory distress syndrome (RDS) and who had received exogenous bovine lipid extracted surfactant on the first day of life was ...
Griese, Matthias, Westerburg, Bettina
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Familial idiopathic pulmonary fibrosis in a young female
Respiratory Medicine Case Reports, 2018 Idiopathic pulmonary fibrosis is a chronic interstitial lung disease of unknown cause. In the past years there have been observations of clustering of pulmonary fibrosis in families, indicating the disease can be inherited.
Sajitha S. Sritharan +4 more
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Rationale for Prolonged Glucocorticoid Use in Pediatric ARDS: What the Adults Can Teach Us. [PDF]
, 2016 Based on molecular mechanisms and physiologic data, a strong association has been established between dysregulated systemic inflammation and progression of acute respiratory distress syndrome (ARDS).
Meduri, Gianfranco Umberto +1 more
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Archives of Medical Science, 2020 Introduction The comparative efficacy of pulmonary surfactant in the treatment of respiratory distress syndrome in preterm infants remains unclear. We aimed to evaluate the effectiveness of different pulmonary surfactant in the treatment of respiratory ...
Caihong Qiu +4 more
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Bio-inspired pulmonary surfactant-modified nanogels : a promising siRNA delivery system [PDF]
, 2015 Inhalation therapy with small interfering RNA (siRNA) is a promising approach in the treatment of pulmonary disorders. However, clinical translation is severely limited by the lack of suitable delivery platforms.
Braeckmans, Kevin +5 more
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Mavrilimumab, a fully human granulocyte-macrophage colony-stimulating factor receptor α monoclonal antibody: long-term safety and efficacy in patients with rheumatoid arthritis [PDF]
, 2018 Objective: Mavrilimumab, a human monoclonal antibody, targets granulocyte-macrophage colony-stimulating factor receptor alpha. We report mavrilimumab long-term safety and efficacy in rheumatoid arthritis patients in two phase IIb studies (1071, 1107 ...
Achuthan +44 more
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Biosynthesis of phosphatidylcholine by human lysophosphatidylcholine acyltransferase 11
Journal of Lipid Research, 2009 Pulmonary surfactant is a complex of phospholipids and proteins lining the alveolar walls of the lung. It reduces surface tension in the alveoli, and is critical for normal respiration.
Takeshi Harayama +2 more
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A finite membrane element formulation for surfactants
, 2019 Surfactants play an important role in various physiological and biomechanical applications. An example is the respiratory system, where pulmonary surfactants facilitate the breathing and reduce the possibility of airway blocking by lowering the surface ...
Roohbakhshan, Farshad, Sauer, Roger A.
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