Results 41 to 50 of about 74,178 (294)

Lung Surfactant Lipids Provide Immune Protection Against Haemophilus influenzae Respiratory Infection

Frontiers in Immunology, 2019
Non-typeable Haemophilus influenzae (NTHi) causes persistent respiratory infections in patients with chronic obstructive pulmonary disease (COPD), probably linked to its capacity to invade and reside within pneumocytes.
Belén García-Fojeda, Belén García-Fojeda, Zoe González-Carnicero, Alba de Lorenzo, Carlos M. Minutti, Carlos M. Minutti, Lidia de Tapia, Begoña Euba, Begoña Euba, Alba Iglesias-Ceacero, Sonia Castillo-Lluva, Junkal Garmendia, Junkal Garmendia, Cristina Casals, Cristina Casals   +14 more
doaj   +1 more source

Systematic Analysis of Composition, Interfacial Performance and Effects of Pulmonary Surfactant Preparations on Cellular Uptake and Cytotoxicity of Aerosolized Nanomaterials

Small Science, 2021
The interplay of particles with pulmonary surfactant, a lipid‐protein material pivotal for lung function, is hypothesized as a key factor that has not been routinely considered in the current in vitro models when determining the fate of inhaled ...
Benedikt Huck, Alberto Hidalgo, Franziska Waldow, Dominik Schwudke, Karoline I. Gaede, Claus Feldmann, Patrick Carius, Chiara Autilio, Jesus Pérez-Gil, Konrad Schwarzkopf, Xabier Murgia, Brigitta Loretz, Claus-Michael Lehr   +12 more
doaj   +1 more source

Surfactant Treatment Shows Higher Correlation Between Ventilator and EIT Tidal Volumes in an RDS Animal Model

Frontiers in Physiology, 2022
Neonatal respiratory distress syndrome (RDS) is a condition of pulmonary surfactant insufficiency in the premature newborn. As such, artificial pulmonary surfactant administration is a key treatment. Despite continued improvement in the clinical outcomes
Yoon Zi Kim, Hee Yoon Choi, Yong Sung Choi, Chae Young Kim, Young Joo Lee, Sung Hoon Chung   +5 more
doaj   +1 more source

Biophysicochemical interaction of a clinical pulmonary surfactant with nano-alumina

, 2015
We report on the interaction of pulmonary surfactant composed of phospholipids and proteins with nanometric alumina (Al2O3) in the context of lung exposure and nanotoxicity.
Berret, J. -F., Borgne, R. Le, Mousseau, F., Seyrek, E.   +3 more
core   +4 more sources

Xylem surfactants introduce a new element to the cohesion-tension theory [PDF]

, 2016
Vascular plants transport water under negative pressure without constantly creating gas bubbles that would disable their hydraulic systems. Attempts to replicate this feat in artificial systems almost invariably result in bubble formation, except under ...
Do, Aissa YT, Espino, Susana, Jansen, Steven, Michaud, Joseph M, Nima, Neda, Papahadjopoulos-Sternberg, Brigitte, Romo, David M, Schenk, H Jochen, Steppe, Kathy, Yang, Jinlong, Zuo, Yi Y   +10 more
core   +1 more source

The adsorption of biomolecules to multi-walled carbon nanotubes is influenced by both pulmonary surfactant lipids and surface chemistry

Journal of Nanobiotechnology, 2010
Background During production and processing of multi-walled carbon nanotubes (MWCNTs), they may be inhaled and may enter the pulmonary circulation. It is essential that interactions with involved body fluids like the pulmonary surfactant, the blood and ...
Yan Bing, Nelle Mathias, Gehr Peter, Krug Harald F, Rothen-Rutishauser Barbara, Gasser Michael, Wick Peter   +6 more
doaj   +1 more source

Genetic risk factors associated with respiratory distress syndrome [PDF]

Korean Journal of Pediatrics, 2014
Respiratory distress syndrome (RDS) among preterm infants is typically due to a quantitative deficiency of pulmonary surfactant. Aside from the degree of prematurity, diverse environmental and genetic factors can affect the development of RDS.
Heui Seung Jo
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

The role of miR-431-5p in regulating pulmonary surfactant expression in vitro

Cellular & Molecular Biology Letters, 2019
Background Pulmonary surfactant is the complex mixture of lipid and protein that covers the alveolar surface. Pulmonary surfactant deficiency is one of the main causes of neonatal respiratory distress.
Shujun Li, Zhongyi Sun, Tao Chen, Jingjing Pan, Yanqing Shen, Xiaoqing Chen, Xiaoyu Zhou, Rui Cheng, Yang Yang   +8 more
doaj   +1 more source