Results 41 to 50 of about 1,493,409 (315)

In vitro characterization and in vivo comparison of the pulmonary outcomes of Poractant alfa and Calsurf in ventilated preterm rabbits.

PLoS ONE, 2020
Poractant alfa and Calsurf are two natural surfactants widely used in China for the treatment of neonatal respiratory distress syndrome, which are extracted from porcine and calf lungs, respectively.
Xiaojing Guo, Siwei Luo, Davide Amidani, Claudio Rivetti, Giuseppe Pieraccini, Barbara Pioselli, Silvia Catinella, Xabi Murgia, Fabrizio Salomone, Yaling Xu, Ying Dong, Bo Sun   +11 more
doaj   +1 more source

The Scientific Network of Surfactants: Structural Analysis [PDF]

, 2006
The scientific network of the surfactants and related subjects has been analyzed with the CoPalRed© knowledge system. The actors studied have been countries, research centers and laboratories, researchers, and journals.
Ruiz-Baños, Rosario, Rosario Ruiz‐Baños, Jurado-Alameda, Encarnación, Rafael Bailón‐Moreno, Bailón-Moreno, Rafael, Encarnación Jurado‐Alameda   +5 more
core   +1 more source

Exogenous pulmonary surfactant: A review focused on adjunctive therapy for severe acute respiratory syndrome coronavirus 2 including SP-A and SP-D as added clinical marker

Current Opinion in Colloid & Interface Science, 2020
Type I and type II pneumocytes are two forms of epithelial cells found lining the alveoli in the lungs. Type II pneumocytes exclusively secrete ‘pulmonary surfactants,’ a lipoprotein complex made up of 90% lipids (mainly phospholipids) and 10% surfactant
Amit Ghati, Paulami Dam, Didar Tasdemir, Ahmet Katı, H. Sellami, G. Sezgin, N. Ildız, O. L. Franco, A. Mandal, I. Ocsoy   +9 more
semanticscholar   +1 more source

Procedural success and safety of a standardized less invasive surfactant administration protocol using fentanyl premedication and video laryngoscopy in preterm infants <32 weeks’ gestation

Frontiers in Pediatrics
BackgroundLess Invasive Surfactant Administration (LISA) has been established for treating respiratory distress syndrome (RDS) in preterm infants, but the impact of pharmacological analgesia or video laryngoscopy on procedural success and safety remains ...
Mircea-Horia Popa-Todirenchi, Benedikt Bubl, Fabian Keller, Marta Busso, Sophie Jaisli, Lisa Marie Bünte, Marc-Alexander Oestreich, Marc-Alexander Oestreich, André Kidszun   +8 more
doaj   +1 more source

Budesonide/formoterol enhances the expression of pro Surfactant Protein-B in lungs of COPD patients. [PDF]

PLoS ONE, 2013
Pulmonary surfactants are essential components of lung homeostasis. In chronic obstructive pulmonary disease (COPD), surfactant expression decreases in lungs whereas, there is a paradoxical increase in protein expression in plasma.
Soo Jung Um, Stephen Lam, Harvey Coxson, Shu Fan Paul Man, Don D Sin   +4 more
doaj   +1 more source

YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1

iScience, 2021
Summary: Ventilation is dependent upon pulmonary alveoli lined by two major epithelial cell types, alveolar type-1 (AT1) and 2 (AT2) cells. AT1 cells mediate gas exchange while AT2 cells synthesize and secrete pulmonary surfactants and serve as ...
Jason J. Gokey, John Snowball, Anusha Sridharan, Parvathi Sudha, Joseph A. Kitzmiller, Yan Xu, Jeffrey A. Whitsett   +6 more
doaj   +1 more source

COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation

Mediators of Inflammation, 2021
Causes of mortality from COVID-19 include respiratory failure, heart failure, and sepsis/multiorgan failure. TLR4 is an innate immune receptor on the cell surface that recognizes pathogen-associated molecular patterns (PAMPs) including viral proteins and
Mohamed M. Aboudounya, Richard J. Heads
doaj   +1 more source

A case of autoimmune pulmonary alveolar proteinosis with severe respiratory failure treated with segmental lung lavage and oral statin therapy

Respiratory Medicine Case Reports, 2022
Pulmonary alveolar proteinosis (PAP) is a diffuse lung disease characterized by the accumulation of alveolar surfactants due to dysfunction of granulocyte-macrophage colony-stimulating factor-dependent cholesterol clearance.
Tomotsugu Takano, Keisuke Takeda, Satoshi Nakamura, Genta Akiyama, Nobuhisa Ando, Masashi Komori   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Receptor‐Free Identification of Toxic Gases Enabled by Hygroscopic Aqueous Salt Films

Advanced Functional Materials, EarlyView.
Water as a gas sensor coating sounds impossible—until it stops evaporating. Here, hygroscopic salt solutions (LiCl, LiBr, H3PO4) form non‐drying aqueous films on CNT chemiresistors under ambient air. Gases partition into these liquid layers, sometimes transforming into water, and generate salt‐specific resistance fingerprints across a four‐channel ...
Seongwoo Lee, Yun‐Tae Kim, Hwarang Choi, Sanghwan Park, Seongyeop Lim, Chang Young Lee   +5 more
wiley   +1 more source